Novel Single-Stage Transcervical Submandibular Approach for a Giant Multicompartmental Pterygopalatine Fossa Schwannoma: A Case Report and Surgical Strategy.

IF 2.6 4区 医学 Q3 ONCOLOGY
Cancer Management and Research Pub Date : 2026-07-31 eCollection Date: 2026-01-01 DOI:10.2147/CMAR.S620316
Seyed Reza Mousavi, Majid Reza Farrokhi, Seyed Basir Hashemi, Niloofar Borzou, Gholamreza Motazedian, Keyvan Eghbal, Kamran Hosseini, Hesam Abdolhoseinpour, Saeed Tayebi Khorami
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引用次数: 0

Abstract

Background: Giant schwannomas originating in the pterygopalatine fossa (PPF) with multicompartmental extension pose a considerable surgical challenge.

Case presentation: This report details the management of a 34-year-old female who presented with progressive facial numbness, dysphagia, and unilateral facial asymmetry secondary to a voluminous PPF schwannoma.

Imaging findings: Preoperative imaging characterized a solid-cystic expansile mass with involvement of the maxillary sinus, infratemporal fossa, parapharyngeal space, and the anterolateral craniovertebral junction, including encasement of the internal carotid artery.

Surgical approach: Given the tumor's significant lateral and posterior-inferior extension that precluded a purely endoscopic resection, a tailored transcervical submandibular approach was utilized. This open corridor provided direct lateral access, enabling safe proximal vascular control and permitting meticulous neurovascular dissection.

Results: Gross-total resection was ultimately achieved without the need for mandibular osteotomy or transfacial incisions. The patient's postoperative course was uncomplicated, with preservation of neurological function, and follow-up imaging confirmed complete resection.

Conclusion: This case highlights the novel single-stage transcervical submandibular approach as a viable and effective surgical strategy for select, extensive PPF schwannomas with dominant lateral and neurovascular involvement, serves as a critical alternative when endoscopic access is insufficient. To our knowledge, this is the first report of a single-stage transcervical submandibular resection for a multicompartmental PPF schwannoma with such extensive lateral and vascular involvement, unlike previous studies have described multi-staged procedures for similar complex lesions.

新型单期经颈下颌下入路治疗巨大多室翼腭窝神经鞘瘤:1例报告及手术策略。
背景:起源于翼腭窝(PPF)的巨大神经鞘瘤具有多室延伸,是一个相当大的手术挑战。病例介绍:本报告详细介绍了一名34岁女性的治疗方法,她表现为进行性面部麻木,吞咽困难,单侧面部不对称,继发于大量PPF神经鞘瘤。影像学表现:术前影像学表现为实性囊性扩张性肿块,累及上颌窦、颞下窝、咽旁间隙和颅椎前外侧交界处,包括颈内动脉的包裹。手术入路:考虑到肿瘤明显的外侧和后下延伸,排除了单纯的内镜切除,我们采用了量身定制的经颈下颌下入路。这个开放的通道提供了直接的横向通道,使近端血管控制安全,并允许细致的神经血管解剖。结果:在不需要下颌骨截骨术或经面切口的情况下,最终实现了大体全切除。患者术后过程简单,神经功能保留,随访影像学证实完全切除。结论:该病例强调了新的单期经颈下颌下入路是一种可行且有效的手术策略,用于选择性的,广泛的PPF神经鞘瘤,主要是外侧和神经血管受损伤,当内窥镜进入不足时,可作为一种重要的替代方法。据我们所知,这是第一次对具有如此广泛的外侧和血管累及的多室PPF神经鞘瘤进行单期经颈下颌下切除术的报道,不像以前的研究描述了类似复杂病变的多期手术。
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来源期刊
Cancer Management and Research
Cancer Management and Research Medicine-Oncology
CiteScore
7.40
自引率
0.00%
发文量
448
审稿时长
16 weeks
期刊介绍: Cancer Management and Research is an international, peer reviewed, open access journal focusing on cancer research and the optimal use of preventative and integrated treatment interventions to achieve improved outcomes, enhanced survival, and quality of life for cancer patients. Specific topics covered in the journal include: ◦Epidemiology, detection and screening ◦Cellular research and biomarkers ◦Identification of biotargets and agents with novel mechanisms of action ◦Optimal clinical use of existing anticancer agents, including combination therapies ◦Radiation and surgery ◦Palliative care ◦Patient adherence, quality of life, satisfaction The journal welcomes submitted papers covering original research, basic science, clinical & epidemiological studies, reviews & evaluations, guidelines, expert opinion and commentary, and case series that shed novel insights on a disease or disease subtype.
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