{"title":"Comparative Vector Analysis of Astigmatic Changes After Small-incision Lenticule Extraction versus Femtosecond Laser In -situ Keratomileusis.","authors":"Mai Hong Phan, Luong Minh Huynh, Say Kiang Foo","doi":"10.18502/jovr.v21.18010","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To compare thevisual outcomes of small-incision lenticule extraction (SMILE) versus femtosecond laser in-situ keratomileusis (FS-LASIK) in eyes with myopia and high astigmatism.</p><p><strong>Methods: </strong>This retrospective study was conducted at a tertiary eye hospital between January 2021 and December 2022. Data were collected from individuals with myopia up to <math><mo>-</mo></math> 10.00 diopters (D) and cylinder <math><mo>≥</mo></math> 2.50 D who underwent SMILE (VisuMax 500) or FS-LASIK (MEL 90) and completed a 3-month postoperative follow-up.</p><p><strong>Results: </strong>A total of 170 eyes of 123 patients were included: 83 eyes (60 patients) underwent SMILE, and 87 eyes (63 patients) underwent FS-LASIK. The preoperative cylindrical refractive error was <math><mo>-</mo></math> 3.01 <math><mo>±</mo></math> 0.61 D in the SMILE group and <math><mo>-</mo></math> 3.09 <math><mo>±</mo></math> 0.66 D in the FS-LASIK group. At 3 months, there was no statistically significant difference in uncorrected visual acuity (UCVA) or manifest refraction spherical equivalent (SEQ) between the two groups (<i>P</i> = 0.26 and <i>P</i> = 0.88, respectively). In the SMILE group, 90.4% of eyes achieved an uncorrected distance visual acuity (UDVA) of 20/20 or better compared to 98.77% with a preoperative corrected distance visual acuity (CDVA) of 20/20 or better. In the FS-LASIK group, 80.46% of eyes achieved a UDVA of 20/20 or better compared to 94.25% with a preoperative CDVA of 20/20 or better. Moreover, 95.1% of eyes in the SMILE group and 94.3% in the FS-LASIK group were within <math><mo>±</mo></math> 0.50 D. Vector analysis showed comparable results between the two groups in terms of target-induced astigmatism (<i>P</i> = 0.559), difference vector (<i>P</i> = 0.155), index of success (<i>P</i> = 0.091), and angle of error (<i>P</i> = 0.89). The surgically induced astigmatism and correction index were significantly lower in the SMILE group (<i>P</i> < 0.01), whereas the absolute magnitude of error was higher in the SMILE group (<i>P</i> = 0.02).</p><p><strong>Conclusion: </strong>SMILE and FS-LASIK have comparable efficacy, predictability, and safety in correcting myopia associated with high astigmatism ( <math><mo>≥</mo></math> 2.50 D).</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"21 ","pages":""},"PeriodicalIF":1.4000,"publicationDate":"2026-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13430490/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Ophthalmic & Vision Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18502/jovr.v21.18010","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose: To compare thevisual outcomes of small-incision lenticule extraction (SMILE) versus femtosecond laser in-situ keratomileusis (FS-LASIK) in eyes with myopia and high astigmatism.
Methods: This retrospective study was conducted at a tertiary eye hospital between January 2021 and December 2022. Data were collected from individuals with myopia up to 10.00 diopters (D) and cylinder 2.50 D who underwent SMILE (VisuMax 500) or FS-LASIK (MEL 90) and completed a 3-month postoperative follow-up.
Results: A total of 170 eyes of 123 patients were included: 83 eyes (60 patients) underwent SMILE, and 87 eyes (63 patients) underwent FS-LASIK. The preoperative cylindrical refractive error was 3.01 0.61 D in the SMILE group and 3.09 0.66 D in the FS-LASIK group. At 3 months, there was no statistically significant difference in uncorrected visual acuity (UCVA) or manifest refraction spherical equivalent (SEQ) between the two groups (P = 0.26 and P = 0.88, respectively). In the SMILE group, 90.4% of eyes achieved an uncorrected distance visual acuity (UDVA) of 20/20 or better compared to 98.77% with a preoperative corrected distance visual acuity (CDVA) of 20/20 or better. In the FS-LASIK group, 80.46% of eyes achieved a UDVA of 20/20 or better compared to 94.25% with a preoperative CDVA of 20/20 or better. Moreover, 95.1% of eyes in the SMILE group and 94.3% in the FS-LASIK group were within 0.50 D. Vector analysis showed comparable results between the two groups in terms of target-induced astigmatism (P = 0.559), difference vector (P = 0.155), index of success (P = 0.091), and angle of error (P = 0.89). The surgically induced astigmatism and correction index were significantly lower in the SMILE group (P < 0.01), whereas the absolute magnitude of error was higher in the SMILE group (P = 0.02).
Conclusion: SMILE and FS-LASIK have comparable efficacy, predictability, and safety in correcting myopia associated with high astigmatism ( 2.50 D).