{"title":"Winning the battle against Barrett esophagus and esophageal adenocarcinoma.","authors":"David A Katzka","doi":"10.3949/ccjm.93gr.26054","DOIUrl":null,"url":null,"abstract":"<p><p>Esophageal adenocarcinoma is a highly aggressive cancer that is usually caught too late to avoid severe morbidity and death. Traditional endoscopic screening for adenocarcinoma's precursor-Barrett esophagus-and subsequent surveillance are often ineffective for detecting early cancer, which can often be treated without esophagectomy. Current efforts are focused on better identifying patients at high risk as candidates for endoscopic screening and developing less invasive and cheaper detection methods to enable widespread screening in the primary care setting.</p>","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":"93 8","pages":"467-473"},"PeriodicalIF":5.2000,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cleveland Clinic Journal of Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3949/ccjm.93gr.26054","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Esophageal adenocarcinoma is a highly aggressive cancer that is usually caught too late to avoid severe morbidity and death. Traditional endoscopic screening for adenocarcinoma's precursor-Barrett esophagus-and subsequent surveillance are often ineffective for detecting early cancer, which can often be treated without esophagectomy. Current efforts are focused on better identifying patients at high risk as candidates for endoscopic screening and developing less invasive and cheaper detection methods to enable widespread screening in the primary care setting.
期刊介绍:
The mission of Cleveland Clinic Journal of Medicine (CCJM) is to provide its readers with up-to-date, practical, clinical information relevant to internal medicine, cardiology, and related fields. Consistent with this mission, CCJM focuses on timely review articles and other content that has a continuing-education orientation rather than on original research or case reports. CCJM authors, drawn from Cleveland Clinic and other top medical institutions throughout the world, are asked to identify new findings that are changing the practice of medicine and to advise readers how to apply them in daily patient care. Authors are chosen for their experience, acquired through caring for patients, teaching other physicians, and researching clinical questions.