Bone Fractures in People with Hemophilia.

Abstract

The existing literature on bone fractures in people with hemophilia (PWH) states that they should be treated in the same way as in healthy individuals but with perioperative hemostasis control through intravenous infusion of the deficient coagulation factor (factor VIII in hemophilia A, factor IX in hemophilia B) at appropriate doses and for the necessary duration. It has also been found that fractures in PWH are more frequent than in normal individuals, probably due to suffering from osteoporosis. The healing time for fractures in PWH is similar to that of the general population. It should be noted that some fractures in PWH are pathological due to the presence of hemophilic pseudotumors that cause erosion of the affected bone. These fractures should also be treated as pathological fractures of any other etiology. Finally, the risk of acute compartment syndrome associated with bone fractures in PWH should never be forgotten.