Core decompression augmented with bone marrow aspirate concentrate for refractory distal sesamoid bone pathology in horses: A retrospective clinical study.

IF 1.3 2区 农林科学 Q2 VETERINARY SCIENCES
Veterinary Surgery Pub Date : 2026-10-01 Epub Date: 2026-08-01 DOI:10.1111/vsu.70139
Grigorios Maleas, Mahmoud Mageed, Kristyna Hargitaiova
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引用次数: 0

Abstract

Objective: To determine short- and long-term outcomes of core decompression combined with autologous bone marrow aspirate concentrate (BMAC) in treating moderate-to-severe refractory distal sesamoid bone (DSB) trabecular pathology in horses.

Study design: Retrospective observational study.

Animals: A total of 21 client-owned Warmblood horses with DSB pathology unresponsive to conservative management.

Methods: Preoperative diagnosis included lameness localization by diagnostic analgesia and magnetic resonance imaging (MRI) confirmation of DSB trabecular pathology. Horses underwent arthroscopic core decompression via the palmar recess of the distal interphalangeal joint followed by intraosseous BMAC injection. Outcomes were assessed clinically and by follow-up radiography and MRI.

Results: No major intraoperative or postoperative complications occurred in any of the 21 operated horses. Nine horses met inclusion criteria for long-term follow-up, which included clinical, radiographic, and MRI assessments at 6 months and up to 18 months postoperatively. At 6 months, six of nine horses (67%) were sound and returned to training. MRI follow-up demonstrated reduced short tau inversion recovery (STIR) hyperintensity and increased T1-weighted signal within the DSB trabecular bone, consistent with a reduction in active trabecular bone pathology. Three horses remained lame with unchanged MRI findings. At 18 months, six horses remained sound, and three returned to their previous or intended performance levels. Radiographic remodeling of cyst-like lesions was evident in three cases.

Conclusion: Core decompression augmented with BMAC was well tolerated with no unexpected complications in this cohort. This approach allowed horses with advanced DSB trabecular pathology refractory to conservative therapy return to function.

Clinical impact: This combined surgical-orthobiologic approach may offer a viable therapeutic option for horses with advanced refractory navicular bone pathology.

核心减压强化骨髓抽吸浓缩液治疗马难治性远端籽骨病理:回顾性临床研究。
目的:探讨核心减压联合自体骨髓浓缩液(BMAC)治疗马中重度难治性远端籽骨(DSB)小梁病变的短期和长期疗效。研究设计:回顾性观察性研究。动物:共有21匹客户拥有的温血马,DSB病理对保守治疗无反应。方法:术前诊断包括通过诊断性镇痛定位跛行和DSB小梁病理的磁共振成像(MRI)证实。马通过远端指间关节掌隐窝进行关节镜下核心减压,然后进行骨内BMAC注射。结果通过临床和随访x线摄影和MRI进行评估。结果:21匹马均无重大术中、术后并发症发生。9匹马符合长期随访的纳入标准,包括术后6个月至18个月的临床、放射学和MRI评估。6个月时,9匹马中有6匹(67%)健康并恢复训练。MRI随访显示短tau反转恢复(STIR)高强度降低,DSB骨小梁内t1加权信号增加,与活动性骨小梁病理减少一致。三匹马仍然跛行,MRI检查结果没有变化。在18个月时,6匹马保持健康,3匹恢复到之前或预期的表现水平。3例囊肿样病变的影像学重构明显。结论:在这个队列中,核心减压增强BMAC耐受性良好,没有意外并发症。这种方法使晚期DSB小梁病理对保守治疗难治性的马恢复功能。临床影响:这种外科-骨科联合方法可能为患有晚期难治性舟骨病理的马提供一种可行的治疗选择。
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来源期刊
Veterinary Surgery
Veterinary Surgery 农林科学-兽医学
CiteScore
3.40
自引率
22.20%
发文量
162
审稿时长
8-16 weeks
期刊介绍: Veterinary Surgery, the official publication of the American College of Veterinary Surgeons and European College of Veterinary Surgeons, is a source of up-to-date coverage of surgical and anesthetic management of animals, addressing significant problems in veterinary surgery with relevant case histories and observations. It contains original, peer-reviewed articles that cover developments in veterinary surgery, and presents the most current review of the field, with timely articles on surgical techniques, diagnostic aims, care of infections, and advances in knowledge of metabolism as it affects the surgical patient. The journal places new developments in perspective, encompassing new concepts and peer commentary to help better understand and evaluate the surgical patient.
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