Bonding to Molar-Incisor Hypomineralization Affected Teeth: A Scoping Review of Adhesive Strategies, In Vitro Performance, and Clinical Outcomes.

Abstract

Molarincisor hypomineralization (MIH) poses major restorative challenges due to compromised enamel and its reduced bonding capacity. This scoping review evaluated treatment options for MIHaffected young permanent teeth following PRISMAScR guidelines. A systematic search in PubMed, Cochrane, Science Direct and gray literature identified 21 eligible studies published between 2013 and 2025, including invitro and clinical studies. Laboratory findings demonstrated lower bond strengths in MIH enamel compared with the sound enamel. Etchandrinse adhesives performed more reliably than that of selfetch systems, while pretreatment procedures improved adhesion in some settings. Clinical studies showed resinbased sealants and composites bonded with etchandrinse adhesives achieved higher retention. Glass ionomer and glass hybrid restorations offered mostly short-term success and are best used as an interim option. Investigated indirect restorations provided superior longevity in severe cases. Preventive adjuncts such as applying varnishes reduced hypersensitivity and caries risk. Finally, this review highlights the central role of adhesive performance in MIH management.