Rare subgroup of A phenotype-a case series.

IF 1.4 4区医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL

Asian Biomedicine Pub Date : 2026-06-30 eCollection Date: 2026-06-01 DOI:10.2478/abm-2026-0023

Nur Ilyia Syazwani Saidin, Nurul Anis Che Anuar, Mohd Nazri Hassan, Noor Haslina Mohd Noor, Zefarina Zulkafli, Hisham Atan Edinur

引用次数: 0

Abstract

Testing for ABO incompatibility between a potential blood donor and recipient is the cornerstone of pretransfusion testing. Occasionally, weak agglutination reactions occur due to low expression of A and B antigens on the surface of red blood cells. This can lead to inconsistencies in blood group typing, as seen in a case where a patient's forward and reverse typing showed discrepancies. Following a comprehensive analytical assessment, the patient was identified as having a distinctive variant of blood group A, belonging to the less common subgroups-A₃, A_end, A_x, A_m, A_y, and A_el. Herein, we present 3 case series of ABO subgroups identified through extended ABO blood grouping procedures.

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罕见的A型亚群-病例系列。

检测潜在献血者和受血者之间的ABO血型不相容是输血前检测的基础。偶尔，由于红细胞表面A和B抗原的低表达，会发生弱凝集反应。这可能导致血型分型不一致，正如在一个病例中看到的，病人的正向和反向分型显示差异。经过全面的分析评估，患者被确定为a型血的独特变体，属于较不常见的亚群- a3， Aend, Ax, Am， Ay和Ael。在这里，我们提出了3例系列ABO亚群通过扩展ABO血型鉴定程序。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Asian Biomedicine 医学-医学：研究与实验

CiteScore

1.20

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Asian Biomedicine: Research, Reviews and News (ISSN 1905-7415 print; 1875-855X online) is published in one volume (of 6 bimonthly issues) a year since 2007. [...]Asian Biomedicine is an international, general medical and biomedical journal that aims to publish original peer-reviewed contributions dealing with various topics in the biomedical and health sciences from basic experimental to clinical aspects. The work and authorship must be strongly affiliated with a country in Asia, or with specific importance and relevance to the Asian region. The Journal will publish reviews, original experimental studies, observational studies, technical and clinical (case) reports, practice guidelines, historical perspectives of Asian biomedicine, clinicopathological conferences, and commentaries Asian biomedicine is intended for a broad and international audience, primarily those in the health professions including researchers, physician practitioners, basic medical scientists, dentists, educators, administrators, those in the assistive professions, such as nurses, and the many types of allied health professionals in research and health care delivery systems including those in training.