Clinical and radiographic outcomes in children with or without prescribed bracing for stable thoracolumbar compression fractures.

IF 2.2 3区 医学 Q3 CLINICAL NEUROLOGY
Ross Moseley, Reid Boyce, Amanda Moon Owens, Julia Pazniokas, Todd C Hankinson, Mark A Erickson, Sumeet Garg, Klane K White, Mohammed Alshareef
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引用次数: 0

Abstract

Objective: The role of bracing in stable pediatric thoracolumbar compression fractures remains uncertain, with limited pediatric-specific evidence to guide practice. Therefore, the aim of this study was to determine the impact of prescribed bracing on symptom recovery, return to activity (RTA), radiographic remodeling, and reinjury in children and adolescents with this common injury.

Methods: The authors performed a retrospective cohort analysis with AO Spine type A1 stable vertebral compression fractures treated at a single academic children's hospital in 2016-2025. Inclusion criteria comprised an age ≤ 18 years, radiographically confirmed type A1 thoracic or lumbar compression fracture, and adequate follow-up with radiographic documentation. Outcomes included symptoms at follow-up, RTA clearance, and vertebral height restoration. Cohort comparisons were performed, as were region-stratified analyses. Both univariate and multivariable analyses along with interaction models were performed, and random forest classifiers were trained.

Results: Two hundred three pediatric patients with a median age of 12 years (range 2-18 years) were included in this study. The braced group was slightly older (median age 13 vs 11 years, p = 0.004). Forty-eight percent of the entire cohort was female (52% vs 43%, p = 0.132). Bracing was prescribed in 56% of cases. Injury severity was similar between groups (median height loss: 19.7% braced vs 20.4% unbraced, p = 0.261). At the first follow-up (FU1) 4-6 weeks postinjury, 42% of braced patients remained symptomatic versus 31% of unbraced patients, with braced patients with thoracic fractures showing more than 3 times higher odds of persistent symptoms (OR 3.2, 95% CI 1.48-6.67, p = 0.003). This effect persisted at the second follow-up (FU2) 3-6 months postinjury (p = 0.026). Bracing was also associated with a delayed RTA at FU1 (p = 0.001), although this effect diminished by FU2. Radiographically, braced patients demonstrated vertebral height restoration significantly sooner (brace × time interaction, p = 0.002), but this did not correspond to improved symptoms or function. Reinjury within 1 year was also more common in braced patients (11.5% vs 3.3%, OR 3.77, 95% CI 1.04-13.67, p = 0.04).

Conclusions: In a pediatric cohort with stable thoracolumbar compression fractures, prescribed bracing was not associated with symptomatic or functional improvement and was correlated with delayed recovery and increased reinjury risk, despite accelerated radiographic remodeling. These findings add to the growing literature questioning a default brace prescription in thoracolumbar compression fractures. Future prospective studies will be necessary to validate these findings.

使用或不使用处方支具治疗稳定胸腰椎压缩性骨折的儿童临床和影像学结果
目的:支具在稳定型儿童胸腰椎压缩性骨折中的作用尚不确定,指导实践的儿科特异性证据有限。因此,本研究的目的是确定处方支具对患有这种常见损伤的儿童和青少年的症状恢复、恢复活动(RTA)、影像学重塑和再损伤的影响。方法:作者对2016-2025年在一家学术儿童医院治疗的AO脊柱A1型稳定椎体压缩性骨折进行回顾性队列分析。纳入标准包括年龄≤18岁,影像学证实为A1型胸椎或腰椎压缩性骨折,并有充分的影像学资料随访。结果包括随访时的症状、RTA清除和椎体高度恢复。进行了队列比较和区域分层分析。进行了单变量和多变量分析以及相互作用模型,并训练了随机森林分类器。结果:203例中位年龄为12岁(范围2-18岁)的儿科患者被纳入本研究。支架组年龄稍大(中位年龄13岁vs 11岁,p = 0.004)。整个队列中48%为女性(52% vs 43%, p = 0.132)。56%的病例使用了支具。两组间损伤严重程度相似(中位高度损失:19.7%与20.4%,p = 0.261)。在损伤后4-6周的第一次随访(FU1)中,42%的支架患者仍有症状,而31%的未支架患者仍有症状,支架患者出现持续症状的几率是未支架患者的3倍多(OR 3.2, 95% CI 1.48-6.67, p = 0.003)。这种影响在损伤后3-6个月的第二次随访(FU2)中持续存在(p = 0.026)。支具也与FU1时延迟RTA相关(p = 0.001),尽管这种影响在FU2时减弱。x线摄影显示,支架患者的椎体高度恢复明显更快(支架与时间的相互作用,p = 0.002),但这并不对应于症状或功能的改善。1年内再损伤在支架患者中也更为常见(11.5% vs 3.3%, OR 3.77, 95% CI 1.04-13.67, p = 0.04)。结论:在稳定胸腰椎压缩性骨折的儿童队列中,处方支具与症状或功能改善无关,尽管加速了x线重塑,但与延迟恢复和增加再损伤风险相关。这些发现增加了越来越多的文献对胸腰椎压缩性骨折默认支具处方的质疑。未来的前瞻性研究将有必要验证这些发现。
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来源期刊
Journal of neurosurgery. Pediatrics
Journal of neurosurgery. Pediatrics 医学-临床神经学
CiteScore
3.40
自引率
10.50%
发文量
307
审稿时长
2 months
期刊介绍: Information not localiced
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