J. Angulo Velásquez, M. López Fuentes, D. Cruzado-Sanchez
{"title":"Sarcoma mieloide orbitario como primer signo de presentación de leucemia mieloide aguda en un paciente pediátrico: reporte de caso","authors":"J. Angulo Velásquez, M. López Fuentes, D. Cruzado-Sanchez","doi":"10.1016/j.oftal.2026.502538","DOIUrl":null,"url":null,"abstract":"<div><div>Myeloid sarcoma (MS) is a rare extramedullary tumor composed of immature myeloid cells that may occur in association with acute myeloid leukemia (AML). It is more common in children than in adults, and the orbit represents one of the most frequent sites of involvement. When MS presents as an isolated lesion or precedes the diagnosis of AML, accurate diagnosis may be challenging, potentially delaying treatment and adversely affecting prognosis. We report a case of orbital MS as the initial manifestation of AML in a previously healthy pediatric patient with a rapidly progressive clinical course.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"101 8","pages":"Article 502538"},"PeriodicalIF":0.0000,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archivos De La Sociedad Espanola De Oftalmologia","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0365669126000766","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/4/19 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Myeloid sarcoma (MS) is a rare extramedullary tumor composed of immature myeloid cells that may occur in association with acute myeloid leukemia (AML). It is more common in children than in adults, and the orbit represents one of the most frequent sites of involvement. When MS presents as an isolated lesion or precedes the diagnosis of AML, accurate diagnosis may be challenging, potentially delaying treatment and adversely affecting prognosis. We report a case of orbital MS as the initial manifestation of AML in a previously healthy pediatric patient with a rapidly progressive clinical course.
期刊介绍:
La revista Archivos de la Sociedad Española de Oftalmología, editada mensualmente por la propia Sociedad, tiene como objetivo publicar trabajos de investigación básica y clínica como artículos originales; casos clínicos, innovaciones técnicas y correlaciones clinicopatológicas en forma de comunicaciones cortas; editoriales; revisiones; cartas al editor; comentarios de libros; información de eventos; noticias personales y anuncios comerciales, así como trabajos de temas históricos y motivos inconográficos relacionados con la Oftalmología. El título abreviado es Arch Soc Esp Oftalmol, y debe ser utilizado en bibliografías, notas a pie de página y referencias bibliográficas.