The Role of Photobiomodulation and Light Therapy in Enhancing Burn Wound Recovery

IF 3.5 4区医学 Q2 DERMATOLOGY

Journal of Cosmetic Dermatology Pub Date : 2026-07-28 DOI:10.1111/jocd.71040

Edwin Chrabieh, Mahmoud El Hajj, Saif Emsieh, Hazem Omaish, Mazen Kurban

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引用次数: 0

Abstract

Background

Photobiomodulation (PBM) is a non-invasive treatment using low-intensity red or near-infrared light to stimulate tissue repair and reduce inflammation. While used in aesthetic and rehabilitative medicine, its role in burn wound healing remains underexplored. Given biological parallels between post-injury remodeling and cosmetic rejuvenation, a systematic review of PBM in burn care is warranted.

Aims

To evaluate the clinical effectiveness, safety, and outcomes of PBM—such as low-level laser and light-emitting diode (LED) therapy—in human burn patients.

Methods

A systematic search of Ovid MEDLINE, Embase, and LILACS was conducted up to 2024. The MEDLINE search was conducted via Ovid MEDLINE, which includes all records indexed in PubMed, ensuring comprehensive coverage of the biomedical literature. Studies were included if they investigated PBM in human burn patients and reported at least one clinical outcome. Two reviewers independently screened studies; a third resolved conflicts. Risk of bias was assessed using a modified Cochrane tool. Due to outcome heterogeneity, narrative synthesis was performed. A binary heatmap visualized patterns across six domains: wound area, healing time, pain (VAS), scar quality (VSS), patient satisfaction, and adverse events.

Results

Seven studies involving 190 patients were included. Healing time and pain (VAS) were most frequently reported, followed by wound area and scar quality. Only one study assessed patient satisfaction, and adverse events were inconsistently reported. PBM showed promising effects, including reduced healing time and pain. However, limited comparable data precluded meta-analysis.

Conclusion

PBM appears to be a promising adjunct in burn care, with benefits in healing, pain, and scar remodeling. However, methodological limitations, dosing variability, and inconsistent outcome reporting limit conclusions. High-quality, standardized trials using validated patient-reported outcomes are needed.

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光生物调节和光治疗在促进烧伤创面恢复中的作用

光生物调节（PBM）是一种使用低强度红光或近红外光刺激组织修复和减少炎症的非侵入性治疗。虽然在美学和康复医学中使用，但其在烧伤伤口愈合中的作用仍未得到充分探讨。鉴于损伤后重塑和美容返老还童之间的生物学相似性，对烧伤护理中的PBM进行系统回顾是有必要的。目的评价低水平激光和发光二极管（LED）治疗烧伤患者的临床有效性、安全性和预后。方法系统检索至2024年的Ovid MEDLINE、Embase和LILACS数据库。MEDLINE检索是通过Ovid MEDLINE进行的，它包括了PubMed索引的所有记录，确保了生物医学文献的全面覆盖。如果研究了人类烧伤患者的PBM并报告了至少一项临床结果，则纳入研究。两位审稿人独立筛选研究；第三种是解决冲突。使用改进的Cochrane工具评估偏倚风险。由于结果的异质性，我们进行了叙事综合。二值热图显示了六个领域的可视化模式：伤口面积、愈合时间、疼痛（VAS）、疤痕质量（VSS）、患者满意度和不良事件。结果纳入7项研究，190例患者。愈合时间和疼痛（VAS）是最常见的报告，其次是伤口面积和疤痕质量。只有一项研究评估了患者满意度，不良事件的报道不一致。PBM显示出良好的效果，包括减少愈合时间和疼痛。然而，有限的可比数据妨碍了meta分析。结论：PBM在烧伤治疗中是一种很有前途的辅助治疗方法，对愈合、疼痛和疤痕重塑有好处。然而，方法学的局限性、剂量的可变性和不一致的结果报告限制了结论。需要使用经过验证的患者报告结果的高质量、标准化试验。

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来源期刊

Journal of Cosmetic Dermatology DERMATOLOGY-

CiteScore

4.30

自引率

13.00%

发文量

818

审稿时长

>12 weeks

期刊介绍： The Journal of Cosmetic Dermatology publishes high quality, peer-reviewed articles on all aspects of cosmetic dermatology with the aim to foster the highest standards of patient care in cosmetic dermatology. Published quarterly, the Journal of Cosmetic Dermatology facilitates continuing professional development and provides a forum for the exchange of scientific research and innovative techniques. The scope of coverage includes, but will not be limited to: healthy skin; skin maintenance; ageing skin; photodamage and photoprotection; rejuvenation; biochemistry, endocrinology and neuroimmunology of healthy skin; imaging; skin measurement; quality of life; skin types; sensitive skin; rosacea and acne; sebum; sweat; fat; phlebology; hair conservation, restoration and removal; nails and nail surgery; pigment; psychological and medicolegal issues; retinoids; cosmetic chemistry; dermopharmacy; cosmeceuticals; toiletries; striae; cellulite; cosmetic dermatological surgery; blepharoplasty; liposuction; surgical complications; botulinum; fillers, peels and dermabrasion; local and tumescent anaesthesia; electrosurgery; lasers, including laser physics, laser research and safety, vascular lasers, pigment lasers, hair removal lasers, tattoo removal lasers, resurfacing lasers, dermal remodelling lasers and laser complications.