Refractory urticarial dermatitis successfully treated with mycophenolate mofetil.

IF 0.6 Q3 MEDICINE, GENERAL & INTERNAL

Oxford Medical Case Reports Pub Date : 2026-07-27 eCollection Date: 2026-07-01 DOI:10.1093/omcr/omag140

Hugo J Leme, Marcelo Pacheco Silva, Adelina Costin, Ana Isabel Gouveia, João Alves

引用次数: 0

Abstract

Urticarial dermatitis is an uncommon inflammatory dermatosis characterized by persistent pruritic urticarial and eczematous eruptions associated with a dermal hypersensitivity reaction pattern on histopathology. We report a case of severe refractory urticarial dermatitis resistant to multiple therapies, including corticosteroids, cyclosporine, methotrexate, dapsone and azathioprine, which demonstrated significant clinical improvement following treatment with mycophenolate mofetil. This case highlights the diagnostic challenges of urticarial dermatitis and supports mycophenolate mofetil as a potential therapeutic option in refractory disease.

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霉酚酸酯成功治疗难治性荨麻疹皮炎。

荨麻疹性皮炎是一种罕见的炎症性皮肤病，其特征是持续瘙痒性荨麻疹和湿疹爆发，在组织病理学上与皮肤过敏反应模式有关。我们报告一例严重难治性荨麻疹皮炎，对多种治疗，包括皮质类固醇，环孢素，甲氨蝶呤，氨苯砜和硫唑嘌呤耐药，经霉酚酸酯治疗后，临床表现出显著改善。本病例突出了荨麻疹皮炎的诊断挑战，并支持霉酚酸酯作为难治性疾病的潜在治疗选择。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Oxford Medical Case Reports MEDICINE, GENERAL & INTERNAL-

CiteScore

0.90

自引率

0.00%

发文量

125

审稿时长

19 weeks

期刊介绍： Oxford Medical Case Reports (OMCR) is an open access, peer-reviewed online journal publishing original and educationally valuable case reports that expand the field of medicine. The journal covers all medical specialities including cardiology, rheumatology, nephrology, oncology, neurology, and reproduction, comprising a comprehensive resource for physicians in all fields and at all stages of training. Oxford Medical Case Reports deposits all articles in PubMed Central (PMC). Physicians and researchers can find your work through PubMed , helping you reach the widest possible audience. The journal is also indexed in the Web of Science Core Collection . Oxford Medical Case Reports publishes case reports under the following categories: Allergy Audiovestibular medicine Cardiology and cardiovascular systems Critical care medicine Dermatology Emergency medicine Endocrinology and metabolism Gastroenterology and hepatology Geriatrics and gerontology Haematology Immunology Infectious diseases and tropical medicine Medical disorders in pregnancy Medical ophthalmology Nephrology Neurology Oncology Paediatrics Pain Palliative medicine Pharmacology and pharmacy Psychiatry Radiology, nuclear medicine, and medical imaging Respiratory disorders Rheumatology Sexual and reproductive health Sports Medicine Substance abuse.