Worry and Anxiety in the Era of Early Diagnosis and Disease Modifying Treatment for Alzheimer's Disease.

IF 7.5 2区医学 Q1 PSYCHIATRY

Current Psychiatry Reports Pub Date : 2026-07-27 DOI:10.1007/s11920-026-01704-1

Shana D Stites, Katherine Lee, Carolyn Kuz, David Mandell, Hillary R Bogner, Rebecca Brown

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引用次数: 0

Abstract

Purpose of review: Psychologists and psychiatrists are well-positioned to be at the forefront of addressing the challenges posed by anxiety in early diagnosis and treatment of Alzheimer's disease (AD) dementia that are unfolding in primary care settings. The present article provides a summary of emerging areas in Alzheimer's disease testing and research to guide clinical decisions and research pursuits.

Recent findings: The present article provides an overview of how anxiety is understood in early diagnosis of dementia due to AD, its influence in AD-related mechanisms, and the implications of these findings on current research practices. We conducted focused literature reviews between January and June 2026 and synthesized the information to provide a narrative review. Overall, the clinical roles of anxiety in AD dementia are expanding- from being viewed primarily as reactions to cognitive decline to serving as informative features of the diagnostic process and clinical course of the disease.

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阿尔茨海默病早期诊断与疾病改良治疗时代的担忧与焦虑。

综述目的：心理学家和精神科医生处于解决阿尔茨海默病（AD）痴呆症早期诊断和治疗中焦虑所带来的挑战的最前沿，这种挑战正在初级保健机构中展开。本文总结了阿尔茨海默病测试和研究的新兴领域，以指导临床决策和研究追求。最近的发现：本文概述了焦虑在阿尔茨海默病痴呆的早期诊断中的作用，它在阿尔茨海默病相关机制中的影响，以及这些发现对当前研究实践的意义。我们在2026年1月至6月期间进行了重点文献综述，并综合信息进行了叙述性综述。总的来说，焦虑在阿尔茨海默病痴呆中的临床作用正在扩大——从最初被视为对认知能力下降的反应，到作为疾病诊断过程和临床病程的信息特征。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Psychiatry Reports PSYCHIATRY-

CiteScore

11.30

自引率

3.00%

发文量

审稿时长

6-12 weeks

期刊介绍： This journal aims to review the most important, recently published research in psychiatry. By providing clear, insightful, balanced contributions by international experts, the journal intends to serve all those involved in the care of those affected by psychiatric disorders. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as anxiety, medicopsychiatric disorders, and schizophrenia and other related psychotic disorders. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided.