Hüseyin Oğuzhan Aslantaş, Şehim Kutlay, Haydar Gök, Semra Özkan, Seçilay Güneş, Atilla Halil Elhan
{"title":"Effects of repetitive peripheral magnetic stimulation on poststroke ankle spasticity: a double-blind randomized controlled trial.","authors":"Hüseyin Oğuzhan Aslantaş, Şehim Kutlay, Haydar Gök, Semra Özkan, Seçilay Güneş, Atilla Halil Elhan","doi":"10.55730/1300-0144.6197","DOIUrl":null,"url":null,"abstract":"<p><strong>Background/aim: </strong>Repetitive peripheral magnetic stimulation (rPMS) is a noninvasive, painless therapy aimed at improving spasticity, with a proposed mechanism that involves neuromodulation through somatosensory and proprioceptive afferent stimulation. The present study evaluates the effectiveness of rPMS on ankle plantar flexor spasticity in participants with stroke.</p><p><strong>Materials and methods: </strong>Included in this prospective, double-blind, randomized, sham-controlled study were 50 participants with poststroke ankle plantar flexor spasticity graded 1-3 according to Modified Ashworth Scale (MAS). Participants were randomized into rPMS (n = 25) and sham (n = 25) groups. All participated in a conventional rehabilitation program, while the rPMS group received 10 rPMS sessions over 2 weeks and the sham group received sham rPMS. Assessments at baseline, posttreatment (2nd week), and follow-up (4th week) included MAS, Modified Tardieu Scale (MTS), Barthel Index (stair/mobility), and electrophysiological H/M ratio.</p><p><strong>Results: </strong>A total of 46 participants completed the study. No adverse events related to the stimulation were reported. The rPMS group showed significant improvements in MAS score, MTS angle and grade, and Barthel Index, while no significant changes were observed in the sham group. A significantly greater proportion of participants in the rPMS group (40%) demonstrated MAS score reduction compared to the sham group (4.8%) (p = 0.004). Between-group analysis favored rPMS for MAS and MTS posttreatment and at follow-up. No significant changes in H/M ratios were observed within or between the groups.</p><p><strong>Conclusion: </strong>rPMS can be a valuable adjunct to a traditional rehabilitation program, potentially improving poststroke spasticity. The reductions recorded in MAS and MTS scores in the absence of electrophysiological changes suggest that rPMS may reduce the biomechanical rather than neural component of spasticity. There is a need to define optimal treatment protocols.</p>","PeriodicalId":23361,"journal":{"name":"Turkish Journal of Medical Sciences","volume":"56 3","pages":"632-644"},"PeriodicalIF":1.4000,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13398597/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Turkish Journal of Medical Sciences","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.55730/1300-0144.6197","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Background/aim: Repetitive peripheral magnetic stimulation (rPMS) is a noninvasive, painless therapy aimed at improving spasticity, with a proposed mechanism that involves neuromodulation through somatosensory and proprioceptive afferent stimulation. The present study evaluates the effectiveness of rPMS on ankle plantar flexor spasticity in participants with stroke.
Materials and methods: Included in this prospective, double-blind, randomized, sham-controlled study were 50 participants with poststroke ankle plantar flexor spasticity graded 1-3 according to Modified Ashworth Scale (MAS). Participants were randomized into rPMS (n = 25) and sham (n = 25) groups. All participated in a conventional rehabilitation program, while the rPMS group received 10 rPMS sessions over 2 weeks and the sham group received sham rPMS. Assessments at baseline, posttreatment (2nd week), and follow-up (4th week) included MAS, Modified Tardieu Scale (MTS), Barthel Index (stair/mobility), and electrophysiological H/M ratio.
Results: A total of 46 participants completed the study. No adverse events related to the stimulation were reported. The rPMS group showed significant improvements in MAS score, MTS angle and grade, and Barthel Index, while no significant changes were observed in the sham group. A significantly greater proportion of participants in the rPMS group (40%) demonstrated MAS score reduction compared to the sham group (4.8%) (p = 0.004). Between-group analysis favored rPMS for MAS and MTS posttreatment and at follow-up. No significant changes in H/M ratios were observed within or between the groups.
Conclusion: rPMS can be a valuable adjunct to a traditional rehabilitation program, potentially improving poststroke spasticity. The reductions recorded in MAS and MTS scores in the absence of electrophysiological changes suggest that rPMS may reduce the biomechanical rather than neural component of spasticity. There is a need to define optimal treatment protocols.
期刊介绍:
Turkish Journal of Medical sciences is a peer-reviewed comprehensive resource that provides critical up-to-date information on the broad spectrum of general medical sciences. The Journal intended to publish original medical scientific papers regarding the priority based on the prominence, significance, and timeliness of the findings. However since the audience of the Journal is not limited to any subspeciality in a wide variety of medical disciplines, the papers focusing on the technical details of a given medical subspeciality may not be evaluated for publication.