Effects of repetitive peripheral magnetic stimulation on poststroke ankle spasticity: a double-blind randomized controlled trial.

IF 1.4 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL
Turkish Journal of Medical Sciences Pub Date : 2026-02-01 eCollection Date: 2026-01-01 DOI:10.55730/1300-0144.6197
Hüseyin Oğuzhan Aslantaş, Şehim Kutlay, Haydar Gök, Semra Özkan, Seçilay Güneş, Atilla Halil Elhan
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引用次数: 0

Abstract

Background/aim: Repetitive peripheral magnetic stimulation (rPMS) is a noninvasive, painless therapy aimed at improving spasticity, with a proposed mechanism that involves neuromodulation through somatosensory and proprioceptive afferent stimulation. The present study evaluates the effectiveness of rPMS on ankle plantar flexor spasticity in participants with stroke.

Materials and methods: Included in this prospective, double-blind, randomized, sham-controlled study were 50 participants with poststroke ankle plantar flexor spasticity graded 1-3 according to Modified Ashworth Scale (MAS). Participants were randomized into rPMS (n = 25) and sham (n = 25) groups. All participated in a conventional rehabilitation program, while the rPMS group received 10 rPMS sessions over 2 weeks and the sham group received sham rPMS. Assessments at baseline, posttreatment (2nd week), and follow-up (4th week) included MAS, Modified Tardieu Scale (MTS), Barthel Index (stair/mobility), and electrophysiological H/M ratio.

Results: A total of 46 participants completed the study. No adverse events related to the stimulation were reported. The rPMS group showed significant improvements in MAS score, MTS angle and grade, and Barthel Index, while no significant changes were observed in the sham group. A significantly greater proportion of participants in the rPMS group (40%) demonstrated MAS score reduction compared to the sham group (4.8%) (p = 0.004). Between-group analysis favored rPMS for MAS and MTS posttreatment and at follow-up. No significant changes in H/M ratios were observed within or between the groups.

Conclusion: rPMS can be a valuable adjunct to a traditional rehabilitation program, potentially improving poststroke spasticity. The reductions recorded in MAS and MTS scores in the absence of electrophysiological changes suggest that rPMS may reduce the biomechanical rather than neural component of spasticity. There is a need to define optimal treatment protocols.

重复外周磁刺激对脑卒中后踝关节痉挛的影响:一项双盲随机对照试验。
背景/目的:重复性外周磁刺激(rPMS)是一种无创、无痛的治疗方法,旨在改善痉挛,其机制涉及通过体感和本体感觉传入刺激进行神经调节。本研究评估rPMS对卒中患者踝关节足底屈肌痉挛的有效性。材料和方法:这项前瞻性、双盲、随机、假对照研究纳入了50名卒中后踝关节足底屈肌痉挛患者,根据改良Ashworth量表(MAS)评分为1-3级。参与者随机分为rPMS组(n = 25)和sham组(n = 25)。所有人都参加了传统的康复计划,而rPMS组在2周内接受了10次rPMS治疗,假组接受假rPMS治疗。基线、治疗后(第2周)和随访(第4周)的评估包括MAS、改良Tardieu量表(MTS)、Barthel指数(楼梯/活动能力)和电生理H/M比。结果:共有46名参与者完成了研究。没有与刺激相关的不良事件的报道。rPMS组在MAS评分、MTS角度和分级、Barthel指数方面均有显著改善,而sham组无显著变化。与假手术组(4.8%)相比,rPMS组有更大比例的参与者(40%)表现出MAS评分降低(p = 0.004)。组间分析支持MAS和MTS治疗后和随访时的rPMS。在组内或组间均未观察到H/M比值的显著变化。结论:rPMS可以作为传统康复计划的一种有价值的辅助手段,潜在地改善脑卒中后痉挛。在没有电生理变化的情况下,MAS和MTS评分的下降表明,rPMS可能会减少痉挛的生物力学成分,而不是神经成分。有必要确定最佳治疗方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Turkish Journal of Medical Sciences
Turkish Journal of Medical Sciences 医学-医学:内科
CiteScore
4.60
自引率
4.30%
发文量
143
审稿时长
3-8 weeks
期刊介绍: Turkish Journal of Medical sciences is a peer-reviewed comprehensive resource that provides critical up-to-date information on the broad spectrum of general medical sciences. The Journal intended to publish original medical scientific papers regarding the priority based on the prominence, significance, and timeliness of the findings. However since the audience of the Journal is not limited to any subspeciality in a wide variety of medical disciplines, the papers focusing on the technical  details of a given medical  subspeciality may not be evaluated for publication.
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