Perspectives for future space biomedical research to ensure crew health and performance for future human space exploration missions beyond Low-Earth Orbit, a multidisciplinary approach

Abstract

To advance Space Exploration, key players across the Space Sector have launched initiatives to boost scientific research and technology development, increasing the Technology Readiness Level. The Spaceship France team from French Space Agency (CNES) was created in 2019 to support these efforts in cooperation with the European Space Agency (ESA). In November 2023, SpaceshipFR from CNES and the French Institute for Space Medicine and Physiology (MEDES) hosted a 2-day workshop to develop a roadmap for research on astronaut health and performance for deep space exploration missions. Emphasis was placed on fostering interdisciplinary collaboration, bringing together experts from diverse fields such as medicine, space science, engineering, artificial intelligence, robotics, and human factors. A variety of methodologies were used to tap into the collective intelligence of participants for generating innovative ideas. The outcome of the workshop was the identification of six pivotal topics, including the development of an integrated intelligent health support system, the creation of an astronaut digital twin combined with AI for health, augmented astronaut solutions, individual and collective behavioural health and performance initiatives, and exploration of hibernation possibilities. Each area addresses specific facets of medical challenges anticipated during Moon or Mars missions, with a focus on leveraging cutting-edge technologies. Following the workshop, teams of experts were formed to develop projects based on these themes. This research roadmap serves as a blueprint for advancing biomedical research and medical capabilities, vital for long-term space mission success and sustainability.