A metabolic organizer directs debneyol biosynthesis and broad-spectrum immunity in solanaceae

IF 8.1 Q1 PLANT SCIENCES

Plant Stress Pub Date : 2026-07-01 Epub Date: 2026-06-24 DOI:10.1016/j.stress.2026.101455

Xinghan Wu, Chen Wang, Jianping Chen, Zongtao Sun

引用次数: 0

Abstract

Debneyol is a phytoalexin mainly reported in Solanaceae plants and has been confirmed to possess broad-spectrum-disease resistance. However, nearly half a century after its discovery, the debneyol pathway and regulatory mechanisms remain unclear. In a recent study published in Cell, Wang et al. for the first time fully elucidated the biosynthetic pathway of debneyol, resolving a long-standing puzzle in phytoalexin-mediated plant chemical defense and laying a foundation for the industrial production of debneyol as well as fitness-cost-free broad -spectrum disease resistance breeding.

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在茄科植物中，代谢组织者指导豆蔻醇的生物合成和广谱免疫

茄内醇是一种主要报道于茄科植物中的植物抗菌素，已被证实具有广谱抗病性。然而，在其发现近半个世纪后，debneyol通路和调控机制仍不清楚。最近，Wang等人在Cell杂志上发表的一篇研究中，首次全面阐明了debneyol的生物合成途径，解决了植物抗毒素介导的植物化学防御中一个长期存在的难题，为debneyol的工业化生产和无健康成本的广谱抗病育种奠定了基础。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Plant Stress PLANT SCIENCES-

CiteScore

5.20

自引率

8.00%

发文量

审稿时长

63 days

期刊介绍： The journal Plant Stress deals with plant (or other photoautotrophs, such as algae, cyanobacteria and lichens) responses to abiotic and biotic stress factors that can result in limited growth and productivity. Such responses can be analyzed and described at a physiological, biochemical and molecular level. Experimental approaches/technologies aiming to improve growth and productivity with a potential for downstream validation under stress conditions will also be considered. Both fundamental and applied research manuscripts are welcome, provided that clear mechanistic hypotheses are made and descriptive approaches are avoided. In addition, high-quality review articles will also be considered, provided they follow a critical approach and stimulate thought for future research avenues. Plant Stress welcomes high-quality manuscripts related (but not limited) to interactions between plants and: Lack of water (drought) and excess (flooding), Salinity stress, Elevated temperature and/or low temperature (chilling and freezing), Hypoxia and/or anoxia, Mineral nutrient excess and/or deficiency, Heavy metals and/or metalloids, Plant priming (chemical, biological, physiological, nanomaterial, biostimulant) approaches for improved stress protection, Viral, phytoplasma, bacterial and fungal plant-pathogen interactions. The journal welcomes basic and applied research articles, as well as review articles and short communications. All submitted manuscripts will be subject to a thorough peer-reviewing process.