Epidemiology and clinical features of acute coronary syndrome patients in selected hospitals in Greece: the CALLINICUS-Hellas registry.

IF 4 4区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Acta cardiologica Pub Date : 2026-07-23 DOI:10.1080/00015385.2026.2706281

Demosthenes Panagiotakos, Donatos Tsamoulis, Vasileios Bouratzis, Ioannis Leventis, Charalampos Kalantzis, Dimitrios Tasoulas, Petros Kalogeras, Belkis Malkots, Stylianos Daios, Georgios Zormpas, Despina Benetou, Andriani Nikolaou, Andreas Ntalaoutis, Alexandros Sianis, Sofia Xanthopoulou, Zinovia Tsantikidi, Anastasios Papoutsoglou, Stylianos Rallidis, Pantelis Gounopoulos, Evagelos Zacharis, Konstantinos Kostopoulos, Sotirios Patsilinakos, Athanasios Trikas, Christodoulos Papadopoulos, Antonios Ziakas, Kimon Stamatelopoulos, Katerina Naka, Dimitrios Tziakas, Ioannis Skoularigis, Charalambos Vlachopoulos, Loukianos S Rallidis

{"title":"Epidemiology and clinical features of acute coronary syndrome patients in selected hospitals in Greece: the CALLINICUS-Hellas registry.","authors":"Demosthenes Panagiotakos, Donatos Tsamoulis, Vasileios Bouratzis, Ioannis Leventis, Charalampos Kalantzis, Dimitrios Tasoulas, Petros Kalogeras, Belkis Malkots, Stylianos Daios, Georgios Zormpas, Despina Benetou, Andriani Nikolaou, Andreas Ntalaoutis, Alexandros Sianis, Sofia Xanthopoulou, Zinovia Tsantikidi, Anastasios Papoutsoglou, Stylianos Rallidis, Pantelis Gounopoulos, Evagelos Zacharis, Konstantinos Kostopoulos, Sotirios Patsilinakos, Athanasios Trikas, Christodoulos Papadopoulos, Antonios Ziakas, Kimon Stamatelopoulos, Katerina Naka, Dimitrios Tziakas, Ioannis Skoularigis, Charalambos Vlachopoulos, Loukianos S Rallidis","doi":"10.1080/00015385.2026.2706281","DOIUrl":null,"url":null,"abstract":"Background: the aim of this study is to evaluate features of acute coronary syndrome (ACS) patients, in Greece, using information from a nationwide registry, the Clinical events and Adherence to Lipid LowerINg therapy In aCUte coronary Syndrome (CALLINICUS)-Hellas registry.Methods: CALLINICUS-Hellas Registry is an ongoing, national, multicentre observational registry that aims to evaluate features and incidence of ACS patients in Greece. From January 2022 to December 2025, 2,661 consecutive ACS patients (2,151 males, 60 ± 11 years, 510 females, 63 ± 11 years) were enrolled in the selected collaborating cardiology clinics (15-55% participation rate). Four-point Major Adverse Cardiovascular Event (MACE) including cardiovascular death, myocardial infarction (ST-elevation myocardial infarction [STEMI] and non-STEMI [NSTEMI]), ischaemic stroke and unstable angina (UA) requiring hospitalisation was the outcome of interest at 6-months follow-up.Results: The most common ACS manifestation was NSTEMI (48%) in both sexes, followed by STEMI (37.4%) and UA (13.1%). The male-to-female ratio was approximately 4-to-1. The sex ratio favours males before age 60 years but shifts towards females thereafter. The mean age of ACS was 60 years in males, and 63 years in females. Almost 1 in 4 male and 1 in 6 female ACS patients had a previous cardiovascular event. At 6-months follow-up of 2,068 patients, MACE was observed in 120 patients (5.8%), and the most common manifestation was NSTEMI followed by UA.Conclusions: By addressing the lack of recent registry data, the present study provides an updated description of the demographic, lifestyle, clinical, and healthcare characteristics of ACS patients treated in selected Greek hospitals, offering contemporary insights that may inform future research and healthcare planning.","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-10"},"PeriodicalIF":4.0000,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta cardiologica","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/00015385.2026.2706281","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}

引用次数: 0

Abstract

Background: the aim of this study is to evaluate features of acute coronary syndrome (ACS) patients, in Greece, using information from a nationwide registry, the Clinical events and Adherence to Lipid LowerINg therapy In aCUte coronary Syndrome (CALLINICUS)-Hellas registry.

Methods: CALLINICUS-Hellas Registry is an ongoing, national, multicentre observational registry that aims to evaluate features and incidence of ACS patients in Greece. From January 2022 to December 2025, 2,661 consecutive ACS patients (2,151 males, 60 ± 11 years, 510 females, 63 ± 11 years) were enrolled in the selected collaborating cardiology clinics (15-55% participation rate). Four-point Major Adverse Cardiovascular Event (MACE) including cardiovascular death, myocardial infarction (ST-elevation myocardial infarction [STEMI] and non-STEMI [NSTEMI]), ischaemic stroke and unstable angina (UA) requiring hospitalisation was the outcome of interest at 6-months follow-up.

Results: The most common ACS manifestation was NSTEMI (48%) in both sexes, followed by STEMI (37.4%) and UA (13.1%). The male-to-female ratio was approximately 4-to-1. The sex ratio favours males before age 60 years but shifts towards females thereafter. The mean age of ACS was 60 years in males, and 63 years in females. Almost 1 in 4 male and 1 in 6 female ACS patients had a previous cardiovascular event. At 6-months follow-up of 2,068 patients, MACE was observed in 120 patients (5.8%), and the most common manifestation was NSTEMI followed by UA.

Conclusions: By addressing the lack of recent registry data, the present study provides an updated description of the demographic, lifestyle, clinical, and healthcare characteristics of ACS patients treated in selected Greek hospitals, offering contemporary insights that may inform future research and healthcare planning.

查看原文本刊更多论文

希腊选定医院急性冠状动脉综合征患者的流行病学和临床特征：CALLINICUS-Hellas登记

背景：本研究的目的是评估希腊急性冠脉综合征（ACS）患者的特征，使用来自全国登记的信息，急性冠脉综合征(CALLINICUS)-Hellas登记的临床事件和对降脂治疗的依从性。方法：CALLINICUS-Hellas Registry是一项正在进行的全国性多中心观察性注册，旨在评估希腊ACS患者的特征和发病率。从2022年1月至2025年12月，在选定的合作心脏科诊所连续纳入2661例ACS患者（男性2151例，60±11岁，女性510例，63±11岁）（参与率15-55%）。4点主要心血管不良事件（MACE），包括心血管死亡、心肌梗死（st段抬高型心肌梗死[STEMI]和非STEMI [NSTEMI]）、缺血性卒中和需要住院治疗的不稳定型心绞痛（UA），是6个月随访时关注的结果。结果：男女ACS最常见的表现是NSTEMI(48%)，其次是STEMI（37.4%）和UA（13.1%）。男女比例约为4:1。性别比例在60岁之前偏向男性，60岁之后偏向女性。ACS患者男性平均年龄60岁，女性平均年龄63岁。几乎四分之一的男性和六分之一的女性ACS患者既往有心血管事件。在对2068例患者6个月的随访中，有120例患者（5.8%）出现MACE，最常见的表现是NSTEMI，其次是UA。结论：通过解决缺乏近期登记数据的问题，本研究提供了在选定的希腊医院治疗的ACS患者的人口统计、生活方式、临床和医疗保健特征的最新描述，为未来的研究和医疗保健计划提供了新的见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Acta cardiologica 医学-心血管系统

CiteScore

2.50

自引率

12.50%

发文量

115

审稿时长

2 months

期刊介绍： Acta Cardiologica is an international journal. It publishes bi-monthly original, peer-reviewed articles on all aspects of cardiovascular disease including observational studies, clinical trials, experimental investigations with clear clinical relevance and tutorials.