Deep eutectic solvent-mediated medical dressings: the evolution from green processing solvents to multifunctional integrated media

IF 10.6 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Green Chemistry Pub Date : 2026-07-06 Epub Date: 2026-06-10 DOI:10.1039/d6gc01943a

Zexin Lin, Caiyue Le, Zhixia Li, Dan Kong, Yani Guo, Yimin Sun

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引用次数: 0

Abstract

Deep eutectic solvents (DESs) represent an emerging class of environmentally friendly solvents formed via the complexation of hydrogen bond donors and acceptors. Owing to their superior solvation capabilities, structural tunability, and intrinsic bioactivity, DESs hold considerable promise for reshaping the development of advanced medical dressings. This review systematically summarizes the technological evolution of DESs from conventional processing solvents to multifunctional integrated media. Furthermore, the versatile applications of DESs are comprehensively discussed, encompassing their roles as functional platforms, structure-directing and dynamic crosslinking agents, drug carriers for controlled release, and electroconductive and sensing elements. Subsequently, the current challenges in processing DES-mediated fiber-based medical dressings are outlined. Additionally, a conceptual design for next-generation smart dressings based on a “dry storage–in situ activation” strategy is proposed, offering new insights to facilitate the clinical translation of high-performance dressings.

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深共晶溶剂介质医用敷料：从绿色加工溶剂到多功能集成介质的演变

深共晶溶剂（DESs）是一类新兴的环境友好型溶剂，通过氢键供体和受体络合而形成。由于其优越的溶剂化能力，结构可调节性和内在的生物活性，DESs在重塑先进医用敷料的发展方面具有相当大的前景。本文系统总结了DESs从传统加工溶剂到多功能集成介质的技术发展历程。此外，还全面讨论了DESs的多种应用，包括其作为功能平台，结构导向和动态交联剂，控释药物载体以及导电和传感元件的作用。随后，概述了目前在加工des介导的纤维基医用敷料方面面临的挑战。此外，提出了基于“干储存原位激活”策略的下一代智能敷料的概念设计，为促进高性能敷料的临床转化提供了新的见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Green Chemistry 化学-化学综合

CiteScore

16.10

自引率

7.10%

发文量

677

审稿时长

1.4 months

期刊介绍： Green Chemistry is a journal that provides a unique forum for the publication of innovative research on the development of alternative green and sustainable technologies. The scope of Green Chemistry is based on the definition proposed by Anastas and Warner (Green Chemistry: Theory and Practice, P T Anastas and J C Warner, Oxford University Press, Oxford, 1998), which defines green chemistry as the utilisation of a set of principles that reduces or eliminates the use or generation of hazardous substances in the design, manufacture and application of chemical products. Green Chemistry aims to reduce the environmental impact of the chemical enterprise by developing a technology base that is inherently non-toxic to living things and the environment. The journal welcomes submissions on all aspects of research relating to this endeavor and publishes original and significant cutting-edge research that is likely to be of wide general appeal. For a work to be published, it must present a significant advance in green chemistry, including a comparison with existing methods and a demonstration of advantages over those methods.