First Case Report of a Dog With Intracranial Granular Cell Tumor Treated With Stereotactic Radiotherapy.

IF 1.2 2区农林科学 Q2 VETERINARY SCIENCES

Veterinary Radiology & Ultrasound Pub Date : 2026-07-01 DOI:10.1111/vru.70228

Keiko Murakami, Nicholas J Rancilio, Tyler A Harm, Ariel S Nenninger, Susan E Hollman

引用次数: 0

Abstract

A 12-year-old male castrated Shih Tzu presented with a suspected intracranial granular cell tumor (GCT) in the left cerebrum. The clinical signs had resolved post stereotactic radiotherapy (SRT) of 3 consecutive days of 8 Gy, and serial magnetic resonance imaging (MRI) revealed maximum 56.8% tumor volume reduction 9 months post SRT. Serial MRI showed progressive cerebral microbleeds. The patient neurologically declined 18 months after SRT and was euthanized. A full necropsy, cytologic, and histologic analysis confirmed the diagnosis of GCT. This is the first reported canine case with cytologically and histologically confirmed intracranial GCT treated with SRT with serial MRI at regular intervals following treatment.

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立体定向放疗治疗犬颅内颗粒细胞瘤1例报告。

摘要一例12岁雄性被阉割的西施犬在左脑发现疑似颅内颗粒细胞瘤（GCT）。连续3天8 Gy立体定向放疗（SRT）后临床症状消失，连续磁共振成像（MRI）显示SRT后9个月肿瘤体积最大缩小56.8%。连续MRI显示进行性脑微出血。患者在SRT后18个月神经功能下降并被安乐死。完整的尸检，细胞学和组织学分析证实了GCT的诊断。这是第一例经SRT治疗的犬颅内GCT的细胞学和组织学证实的病例，治疗后定期进行连续MRI检查。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Veterinary Radiology & Ultrasound 农林科学-兽医学

CiteScore

2.40

自引率

17.60%

发文量

133

审稿时长

8-16 weeks

期刊介绍： Veterinary Radiology & Ultrasound is a bimonthly, international, peer-reviewed, research journal devoted to the fields of veterinary diagnostic imaging and radiation oncology. Established in 1958, it is owned by the American College of Veterinary Radiology and is also the official journal for six affiliate veterinary organizations. Veterinary Radiology & Ultrasound is represented on the International Committee of Medical Journal Editors, World Association of Medical Editors, and Committee on Publication Ethics. The mission of Veterinary Radiology & Ultrasound is to serve as a leading resource for high quality articles that advance scientific knowledge and standards of clinical practice in the areas of veterinary diagnostic radiology, computed tomography, magnetic resonance imaging, ultrasonography, nuclear imaging, radiation oncology, and interventional radiology. Manuscript types include original investigations, imaging diagnosis reports, review articles, editorials and letters to the Editor. Acceptance criteria include originality, significance, quality, reader interest, composition and adherence to author guidelines.