Predictive value of the serum sodium to log(D-dimer) ratio for the risk of all-cause death in patients with chronic heart failure with different ejection fractions.

IF 3.1 3区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

BMC Cardiovascular Disorders Pub Date : 2026-07-20 DOI:10.1186/s12872-026-05609-y

Yujuan Peng, Wei Zhang, Yunhong Yang, Tao Shi, Fazhi Yang, Sirui Yang, Xinuo Ma, Ping Xia, Lixing Chen

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引用次数: 0

Abstract

Background: The ratio of serum sodium to log(D-dimer) (log-SDR) in different types of chronic heart failure (CHF) is not well established.

Methods: A total of 1,221 hospitalized CHF patients from the First Affiliated Hospital of Kunming Medical University between January 2017 and October 2021 were retrospectively analyzed. Patients were categorized into log-SDR-L group (log-SDR < 47.90) and log-SDR-H group (log-SDR ≥ 47.90).Prognostic assessments included Kaplan-Meier survival analysis, Cox survival analyses and time-dependent Receiver operating characteristic (ROC) curves analysis to evaluate predictive performance.

Results: We collected data from 1008 patients with CHF. Kaplan-Meier survival analysis revealed that patients with high log-SDR levels had better overall survival (OS). After multivariate adjustment Cox proportional hazards analysis, the level of log-SDR was still independently related to mortality, regardless of CHF subtype.

Conclusions: log-SDR is an important predictor of all-cause mortality in patients with HF, especially female HFrEF plus HFmrEF(HR:0.927, 95%CI:0.898-0.958, p < 0.001). Lower log-SDR levels are associated with an increased risk of all-cause mortality, irrespective of the HF subtype.

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血清钠与对数（d -二聚体）比对不同射血分数慢性心力衰竭患者全因死亡风险的预测价值

背景：不同类型慢性心力衰竭（CHF）患者血清钠/ d -二聚体（log- sdr）的比值尚不明确。方法：回顾性分析2017年1月至2021年10月昆明医科大学第一附属医院收治的1221例慢性心力衰竭住院患者。将患者分为log-SDR- l组（log-SDR）结果：我们收集了1008例CHF患者的数据。Kaplan-Meier生存分析显示，log-SDR水平高的患者总生存期（OS）较好。多因素调整Cox比例风险分析后，无论何种CHF亚型，log-SDR水平仍与死亡率独立相关。结论：log-SDR是心衰患者全因死亡率的重要预测因子，尤其是女性HFrEF + HFmrEF(HR:0.927, 95%CI:0.898-0.958, p

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来源期刊

BMC Cardiovascular Disorders CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

3.50

自引率

0.00%

发文量

480

审稿时长

1 months

期刊介绍： BMC Cardiovascular Disorders is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of disorders of the heart and circulatory system, as well as related molecular and cell biology, genetics, pathophysiology, epidemiology, and controlled trials.