{"title":"BeanGPT: a domain-specific retrieval-augmented generation system for Phaseolus vulgaris research.","authors":"Kiarash Mirkamandari, Mohsen Yoosefzadeh-Najafabadi","doi":"10.1186/s13007-026-01575-w","DOIUrl":null,"url":null,"abstract":"<p><p>BeanGPT is a domain-specific retrieval augmented generation system designed to support research and breeding decisions in common bean (Phaseolus vulgaris L.) by transforming natural language questions into citation-backed, verifiable answers. The platform integrates a large, curated corpus of legume-focused peer-reviewed literature with structured multi-year agronomic trial records collected across diverse environments, climate projections extending to 2090 under multiple emission scenarios, and standardized cultivar nomenclature to resolve naming inconsistencies across datasets and publications. BeanGPT combines semantic retrieval from a vector database with intent-based query routing and structured parameter extraction to direct questions to genetics, field performance analytics, or climate modules. To reduce errors that commonly occur in general-purpose language models, BeanGPT incorporates a genomic index that enables constant time membership lookup of gene and protein identifiers against authoritative resources, ensuring that molecular entities are either validated or clearly flagged as literature-derived. The system is implemented with a streaming web interface and an asynchronous backend that supports concurrent users and can generate interactive visualizations through automated Plotly code generation. Beta testing demonstrated strong retrieval relevance, low response latency, reliable gene verification, and high citation precision, indicating that domain-grounded RAG can improve accuracy and usability for Phaseolus vulgaris research.</p>","PeriodicalId":20100,"journal":{"name":"Plant Methods","volume":" ","pages":""},"PeriodicalIF":5.2000,"publicationDate":"2026-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13663222/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Plant Methods","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1186/s13007-026-01575-w","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
引用次数: 0
Abstract
BeanGPT is a domain-specific retrieval augmented generation system designed to support research and breeding decisions in common bean (Phaseolus vulgaris L.) by transforming natural language questions into citation-backed, verifiable answers. The platform integrates a large, curated corpus of legume-focused peer-reviewed literature with structured multi-year agronomic trial records collected across diverse environments, climate projections extending to 2090 under multiple emission scenarios, and standardized cultivar nomenclature to resolve naming inconsistencies across datasets and publications. BeanGPT combines semantic retrieval from a vector database with intent-based query routing and structured parameter extraction to direct questions to genetics, field performance analytics, or climate modules. To reduce errors that commonly occur in general-purpose language models, BeanGPT incorporates a genomic index that enables constant time membership lookup of gene and protein identifiers against authoritative resources, ensuring that molecular entities are either validated or clearly flagged as literature-derived. The system is implemented with a streaming web interface and an asynchronous backend that supports concurrent users and can generate interactive visualizations through automated Plotly code generation. Beta testing demonstrated strong retrieval relevance, low response latency, reliable gene verification, and high citation precision, indicating that domain-grounded RAG can improve accuracy and usability for Phaseolus vulgaris research.
期刊介绍:
Plant Methods is an open access, peer-reviewed, online journal for the plant research community that encompasses all aspects of technological innovation in the plant sciences.
There is no doubt that we have entered an exciting new era in plant biology. The completion of the Arabidopsis genome sequence, and the rapid progress being made in other plant genomics projects are providing unparalleled opportunities for progress in all areas of plant science. Nevertheless, enormous challenges lie ahead if we are to understand the function of every gene in the genome, and how the individual parts work together to make the whole organism. Achieving these goals will require an unprecedented collaborative effort, combining high-throughput, system-wide technologies with more focused approaches that integrate traditional disciplines such as cell biology, biochemistry and molecular genetics.
Technological innovation is probably the most important catalyst for progress in any scientific discipline. Plant Methods’ goal is to stimulate the development and adoption of new and improved techniques and research tools and, where appropriate, to promote consistency of methodologies for better integration of data from different laboratories.