Endoluminal lacrimal duct recanalization for pediatric lacrimal duct obstruction: etiologic spectrum and surgical outcomes.

IF 2.7 3区 医学 Q2 OPHTHALMOLOGY
Nozomi Matsumura, Tomoko Ohno, Jutaro Nakamura, Satoshi Goto
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Abstract

Purpose: To clarify the clinical characteristics and etiologic diversity of pediatric lacrimal duct obstruction in children aged ≥1 year requiring surgical treatment under general anesthesia and to evaluate the outcomes of endoluminal lacrimal duct recanalization (ELDR).

Study design: Retrospective observational study.

Methods: All pediatric lacrimal surgical procedures performed under general anesthesia at our institution between 2011 and July 2025 were reviewed. All cases underwent dacryoendoscopic evaluation and treatment. Clinical characteristics, etiologies, and surgical outcomes were analyzed.

Results: The study included 245 patients (338 eyes). Thirty-four eyes (10.1%) had a history of failed probing. Congenital obstruction accounted for 259 eyes (76.6%), acquired obstruction for 38 eyes (11.2%), and syndromic cases for 41 eyes (12.1%). Approximately one-third of all eyes had simple congenital nasolacrimal duct obstruction (CNLDO) caused by membranous distal obstruction. Post-epidemic keratoconjunctivitis obstruction accounted for approximately 10% of cases, for which favorable outcomes were demonstrated following ELDR with intubation. In nonsyndromic cases (congenital and acquired), the success rate, defined as complete resolution, was 97.6% (290/297 eyes). In contrast, syndromic cases demonstrated a significantly lower success rate of 56.1% (23/41 eyes; P < 0.001). No major complications were observed.

Conclusions: The obstruction of the lacrimal duct in pediatric patients requiring surgery under general anesthesia includes a broad spectrum of pathologies beyond simple CNLDO. In patients without congenital malformation syndromes, ELDR was associated with a high success rate and appears to be a safe and effective treatment option for pediatric lacrimal duct obstruction.

儿童泪道阻塞的腔内泪道再通术:病因谱和手术结果。
目的:了解1岁以上需要全麻手术治疗的儿童泪管梗阻的临床特点及病因多样性,评价泪管腔内再通术(ELDR)的效果。研究设计:回顾性观察性研究。方法:回顾2011年至2025年7月在本院全麻下进行的所有儿童泪道手术。所有病例均行泪镜检查和治疗。分析临床特征、病因和手术结果。结果:纳入245例患者(338眼)。34只眼(10.1%)有探诊失败史。先天性梗阻259眼(76.6%),获得性梗阻38眼(11.2%),综合征41眼(12.1%)。大约三分之一的眼睛有单纯性先天性鼻泪管梗阻(CNLDO),由远端膜性梗阻引起。流行后角膜结膜炎梗阻约占病例的10%,ELDR合并插管后显示出良好的结果。在非综合征病例(先天性和获得性)中,成功率(定义为完全消退)为97.6%(290/297眼)。相比之下,综合征病例的成功率明显较低,为56.1%(23/41眼;P < 0.001)。无重大并发症。结论:在全麻下需要手术的儿童泪管阻塞包括广泛的病理,而不仅仅是单纯的CNLDO。在没有先天性畸形综合征的患者中,ELDR与高成功率相关,似乎是儿童泪管阻塞的一种安全有效的治疗选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
4.80
自引率
8.30%
发文量
65
审稿时长
6-12 weeks
期刊介绍: The Japanese Journal of Ophthalmology (JJO) was inaugurated in 1957 as a quarterly journal published in English by the Ophthalmology Department of the University of Tokyo, with the aim of disseminating the achievements of Japanese ophthalmologists worldwide. JJO remains the only Japanese ophthalmology journal published in English. In 1997, the Japanese Ophthalmological Society assumed the responsibility for publishing the Japanese Journal of Ophthalmology as its official English-language publication. Currently the journal is published bimonthly and accepts papers from authors worldwide. JJO has become an international interdisciplinary forum for the publication of basic science and clinical research papers.
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