Use of domino connector to improve simultaneous correction of combined sagittal and coronal malalignment in adult spinal deformity surgery.

IF 3.9 2区 医学 Q2 CLINICAL NEUROLOGY
Lluís Vila, Anouar Bourghli, Daniel Larrieu, Cécile Roscop, Alice Baroncini, Yann Philippe Charles, Ahmet Alanay, Frank Kleinstück, Ferran Pellisé, Javier Pizones, Louis Boissière, Ibrahim Obeid
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引用次数: 0

Abstract

Objective: The objective was to compare the radiological and clinical outcomes of two groups of adult spinal deformity (ASD) patients categorized according to the use or not of a side-to-side domino connector (DC) as a corrective tool for malalignment.

Methods: This study was a retrospective analysis of a prospective multicentric ASD database. Patients with baseline coronal (C7 to central sacral vertical line [CSVL] > 20 mm) and sagittal (pelvic tilt [PT] > 25°, sagittal vertical axis [SVA] > 5 cm, thoracic kyphosis > 60°, or global tilt [GT] > 25°) malalignment who underwent spinal fusion with pelvic fixation and had at least 2 years of follow-up were included. Patients were classified according to the use of DC. To account for baseline differences, a propensity score-matched (PSM) analysis was conducted, matching patients for preoperative deformity magnitude and surgical invasiveness. Finally, a subanalysis of patients without pedicle subtraction osteotomy (PSO) was performed to evaluate the intrinsic corrective power of the DC. Demographic and surgical data, alignment evolution, complications, and patient-reported outcome measures were compared.

Results: Of the 224 patients included, the DC group (n = 81) had significantly worse preoperative biplanar malalignment compared to the no-DC group (n = 143), which led to more frequent use of pedicle subtraction osteotomy (47.7% vs 21.0%, p < 0.001). The DC group achieved significantly greater biplanar correction, including C7-CSVL (29 mm vs 18.7 mm, p = 0.007), GT (22.6° vs 12.0°, p = 0.004), and lumbar lordosis (26° vs 17°, p < 0.05). This translated to superior final sagittal alignment at 2 years, with a lower GT (25.1° vs 29.8°, p = 0.009) and greater L1-S1 lordosis (54.9° vs 48.6°, p < 0.001), while final coronal alignment was comparable between groups. These superior outcomes were confirmed in the PSM analysis, where the DC group retained significantly better postoperative sagittal alignment (p < 0.05). These corrective benefits were also observed in the subgroup of patients who did not undergo 3-column osteotomy, where the DC group maintained significantly greater L1-S1 lordosis (55.5° vs 47.3°, p < 0.001) and thoracic kyphosis (43.1° vs 37.0°, p = 0.032). Despite the greater correction, there was no increase in mechanical complications and patient-reported outcome measures were comparable at the final follow-up.

Conclusions: The use of DC is associated with greater radiological correction of complex sagittal and coronal deformities, with no apparent increase in overall complications rates. These findings suggest that DC may represent a powerful and safe tool for optimizing biplanar correction in challenging ASD cases.

骨牌连接器在成人脊柱畸形手术中同时矫正矢状面和冠状面联合畸形的应用。
目的:目的是比较两组成人脊柱畸形(ASD)患者的放射学和临床结果,这些患者是根据是否使用侧对侧骨牌连接器(DC)作为矫正工具来分类的。方法:本研究对前瞻性多中心ASD数据库进行回顾性分析。基线冠状(C7至骶中央竖线[CSVL] > 20 mm)和矢状(骨盆倾斜[PT] > 25°,矢状垂直轴[SVA] > 5 cm,胸后凸> 60°,或整体倾斜[GT] > 25°)不对准的患者接受脊柱融合骨盆固定,随访至少2年。根据DC的使用情况对患者进行分类。为了解释基线差异,进行了倾向评分匹配(PSM)分析,匹配患者的术前畸形大小和手术侵入性。最后,对没有椎弓根减截骨术(PSO)的患者进行亚分析,以评估DC的内在矫正能力。比较了人口统计学和外科数据、排列演变、并发症和患者报告的结果测量。结果:在纳入的224例患者中,DC组(n = 81)的术前双平面错位明显比无DC组(n = 143)更严重,导致更频繁地使用椎弓根减截骨术(47.7%比21.0%,p < 0.001)。DC组实现了更大的双平面矫正,包括C7-CSVL (29 mm vs 18.7 mm, p = 0.007), GT(22.6°vs 12.0°,p = 0.004)和腰椎前凸(26°vs 17°,p < 0.05)。这转化为2年的最终矢状面对齐,GT较低(25.1°vs 29.8°,p = 0.009), L1-S1前凸较大(54.9°vs 48.6°,p < 0.001),而最终冠状面对齐在两组之间具有可比性。这些优越的结果在PSM分析中得到证实,DC组术后矢状位对齐明显更好(p < 0.05)。在未行3柱截骨术的患者亚组中也观察到这些矫正益处,其中DC组保持了更大的L1-S1前凸(55.5°vs 47.3°,p < 0.001)和胸后凸(43.1°vs 37.0°,p = 0.032)。尽管进行了更大的矫正,但机械并发症没有增加,患者报告的结果在最后随访时是可比的。结论:DC的使用与复杂矢状面和冠状面畸形的放射矫正有关,总体并发症发生率没有明显增加。这些发现表明,DC可能是一种强大而安全的工具,用于优化具有挑战性的ASD病例的双平面矫正。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of neurosurgery. Spine
Journal of neurosurgery. Spine 医学-临床神经学
CiteScore
5.10
自引率
10.70%
发文量
396
审稿时长
6 months
期刊介绍: Primarily publish original works in neurosurgery but also include studies in clinical neurophysiology, organic neurology, ophthalmology, radiology, pathology, and molecular biology.
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