Immune safeguarding as a conserved principle of antiviral defence

IF 104.6 1区生物学 Q1 MICROBIOLOGY

Nature Reviews Microbiology Pub Date : 2026-07-17 DOI:10.1038/s41579-026-01349-0

David Mayo-Muñoz, Eugene V. Koonin, Rafael Pinilla-Redondo, Leise Riber

引用次数: 0

Abstract

All organisms defend against viral infections through active immunity mechanisms that clear the virus or population-level mechanisms that cause regulated cell death. Recent research increasingly shows that, across all domains of life, these two types of defence systems are coupled such that regulated cell death mechanisms safeguard or back up active immunity.

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免疫保护作为抗病毒防御的保守原则

所有生物体都通过主动免疫机制（清除病毒）或群体水平机制（导致受调节的细胞死亡）抵御病毒感染。最近的研究越来越多地表明，在生命的所有领域，这两种类型的防御系统是耦合的，这样受调节的细胞死亡机制保护或支持主动免疫。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Reviews Microbiology 生物-微生物学

CiteScore

74.00

自引率

0.50%

发文量

149

审稿时长

6-12 weeks

期刊介绍： At Nature Reviews Microbiology, our goal is to become the leading source of reviews and commentaries for the scientific community we cater to. We are dedicated to publishing articles that are not only authoritative but also easily accessible, supplementing them with clear and concise figures, tables, and other visual aids. Our objective is to offer an unparalleled service to authors, referees, and readers, and we continuously strive to maximize the usefulness and impact of each article we publish. With a focus on Reviews, Perspectives, and Comments spanning the entire field of microbiology, our wide scope ensures that the work we feature reaches the widest possible audience.