Paadukana Sairaj, Rajendra Pradeepa, Thyparambil Aravindakshan Pramodkumar, Ulagamathesan Venkatesan, Wesley Hannah, Viswanathan Mohan, Ralph Maddison, Ranjit Mohan Anjana, David W Dunstan
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引用次数: 0
Abstract
Rapid changes in urbanization in India have paralleled increased prevalence in noncommunicable diseases (NCDs), including type 2 diabetes (T2D), hypertension (HTN), and obesity. To examine sex-specific temporal trends in the prevalence of T2D, HTN, general obesity (GO), and abdominal obesity (AO) among urban populations in India since 2000, a systematic review and meta-analysis was conducted in accordance with a registered Prospective Register of Systematic Reviews protocol (CRD42024548962). PubMed, Global Health (via EBSCOhost), Embase, Scopus, and Web of Science were searched for studies from 2000-2025 (initial search: October 12, 2024; update: July 4, 2025). Eligible studies were cross-sectional and reported the prevalence of T2D or HTN or obesity in urban Indian populations. Screening, data extraction, and risk-of-bias assessment using the Hoy tool were performed independently by 2 reviewers, with a third resolving conflicts. Pooled prevalence was estimated via random-effects meta-analysis in R (version 4.5.3), with forest and funnel plots generated using ggplot2. Out of 3143 records screened, 57 studies were included. The pooled prevalence demonstrated upward trajectory. T2D rose from 13% in 2000-2005 to 21% in 2021-2025, and HTN from 29% to 31%. For obesity, GO increased from 24% in 2000-2005 to 36% in 2016-2020, while AO rose from 47% to 72% over the same period. Sex-stratified analyses showed greater increases among males for T2D and HTN, whereas AO increased more among females. These findings underscore increasing T2D, HTN, and obesity in urban India, highlighting the need for strengthened primary care and supportive environmental and policy measures address the urban NCD burden.
印度城市化的快速变化与包括2型糖尿病、高血压和肥胖在内的非传染性疾病[NCDs]患病率的增加是同步的。为了研究2000年以来印度城市人群中T2D、HTN、一般性肥胖(GO)和腹部肥胖(AO)患病率的性别特异性时间趋势,根据已注册的PROSPERO协议[CRD42024548962]进行了系统回顾和meta分析。PubMed, Global Health[通过EBSCOhost], Embase, Scopus和Web of Science检索了2000-2025年的研究[初始检索:2024年10月12日;更新日期:2025年7月4日]。符合条件的研究是横断面的,报告了印度城市人群中T2D或HTN或肥胖的患病率。筛选、数据提取和使用Hoy工具的偏倚风险评估由两名审稿人独立完成,第三名审稿人解决冲突。通过R(4.5.3版)中的随机效应荟萃分析估计合并患病率,使用ggplot2生成森林图和漏斗图。在筛选的3143份记录中,纳入了57项研究。总患病率呈上升趋势。T2D从2000-2005年的13%上升到2021-2025年的21%,HTN从29%上升到31%。对于肥胖,氧化石墨烯从2000-2005年的24%上升到2016-2020年的36%,而AO同期从47%上升到72%。性别分层分析显示,T2D和HTN在男性中增加较多,而AO在女性中增加较多。这些发现强调了印度城市中T2D、HTN和肥胖症的增加,强调了加强初级保健和支持性环境和政策措施解决城市非传染性疾病负担的必要性。
期刊介绍:
Epidemiologic Reviews is a leading review journal in public health. Published once a year, issues collect review articles on a particular subject. Recent issues have focused on The Obesity Epidemic, Epidemiologic Research on Health Disparities, and Epidemiologic Approaches to Global Health.