Septic Endophthalmitis Following Suprachoroidal Cyclosporine Implant Placement in Two Horses With Equine Recurrent Uveitis.

Abstract

This article presents the clinical and histopathological findings from two horses that developed severe postoperative complications following suprachoroidal procedures routinely employed in the management of equine recurrent uveitis (ERU). Case 1 was a 5-year-old warmblood stallion that initially received a unilateral suprachoroidal triamcinolone injection, followed later by bilateral suprachoroidal cyclosporine implant (CSI) placement. At 9 weeks postoperatively, the right eye (which had undergone both procedures) developed secondary glaucoma necessitating enucleation. Case 2 was a 14-year-old Appaloosa mare that presented 9 days postoperatively with suspected bilateral CSI rejection. Due to poor visual prognosis, the horse was euthanized. Histopathologic examination of all three affected globes demonstrated findings consistent with severe, suppurative endophthalmitis of bacterial etiology.