Zexi Li, Lingzhi Gao, Dongqi Cai, Nicholas D Lane, Chao Wu
{"title":"Tina: A diffusion neural network for generating personalized AI models from text prompts.","authors":"Zexi Li, Lingzhi Gao, Dongqi Cai, Nicholas D Lane, Chao Wu","doi":"10.1016/j.patter.2026.101571","DOIUrl":null,"url":null,"abstract":"<p><p>Generative artificial intelligence (GenAI) has advanced rapidly across modalities, from text-to-text large language models to text-to-image and text-to-video diffusion models. Here, we investigate text-to-model generation: whether GenAI can map semantic task descriptions to functional neural network parameters for personalized classification. We present Tina, a text-conditioned neural network diffusion model that leverages a diffusion transformer conditioned on contrastive language-image pre-training (CLIP)-embedded task descriptions. Tina generates high-quality personalized classifiers across domains, including natural and medical images, from text prompts at inference time. We demonstrate that Tina achieves both in-distribution and out-of-distribution personalization, supports zero-shot/few-shot image prompts, generalizes to unseen classes, and scales to more complex tasks. Tina establishes text-to-model GenAI as a promising paradigm for on-demand personalization and offers a new channel for human-AI interaction through natural-language instructions.</p>","PeriodicalId":36242,"journal":{"name":"Patterns","volume":"7 7","pages":"101571"},"PeriodicalIF":10.8000,"publicationDate":"2026-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13366521/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Patterns","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.patter.2026.101571","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/7/10 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE","Score":null,"Total":0}
引用次数: 0
Abstract
Generative artificial intelligence (GenAI) has advanced rapidly across modalities, from text-to-text large language models to text-to-image and text-to-video diffusion models. Here, we investigate text-to-model generation: whether GenAI can map semantic task descriptions to functional neural network parameters for personalized classification. We present Tina, a text-conditioned neural network diffusion model that leverages a diffusion transformer conditioned on contrastive language-image pre-training (CLIP)-embedded task descriptions. Tina generates high-quality personalized classifiers across domains, including natural and medical images, from text prompts at inference time. We demonstrate that Tina achieves both in-distribution and out-of-distribution personalization, supports zero-shot/few-shot image prompts, generalizes to unseen classes, and scales to more complex tasks. Tina establishes text-to-model GenAI as a promising paradigm for on-demand personalization and offers a new channel for human-AI interaction through natural-language instructions.