Necessity of calcium and calcitriol supplementation after total thyroidectomy for thyroid carcinoma.

IF 1.1 4区 医学 Q3 OTORHINOLARYNGOLOGY
Ryota Kiwaki, Takemasa Terao, Yorihisa Orita
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Abstract

Objectives: This retrospective observational study aimed to identify factors and predictors associated with the need for lifelong medication after total thyroidectomy for thyroid carcinoma.

Methods: A total of 96 patients who underwent total thyroidectomy for thyroid carcinoma from July 2017 to July 2023 at a tertiary hospital were retrospectively reviewed.

Results: Among the participants, 39 (40.6 per cent) of 96 required long-term calcium and calcitriol supplementation. A smaller number of preserved parathyroid glands during surgery was significantly correlated with the necessity to continue calcium supplementation. Poorly corrected calcium levels on the first post-operative day were significantly associated with the need to continue calcitriol and/or calcium supplementation.

Conclusion: In patients undergoing total thyroidectomy for thyroid carcinoma, careful preservation of the parathyroid glands may reduce the risk of permanent calcium supplementation, whereas an early post-operative decline in serum calcium levels may help identify patients at a higher risk of requiring prolonged medication.

甲状腺癌全甲状腺切除术后补钙和骨化三醇的必要性。
目的:本回顾性观察性研究旨在确定甲状腺癌全甲状腺切除术后需要终身用药的相关因素和预测因素。方法:回顾性分析某三级医院2017年7月至2023年7月行甲状腺癌全切除术的96例患者。结果:在96名参与者中,39名(40.6%)需要长期补充钙和骨化三醇。手术中保留的甲状旁腺数量较少与继续补钙的必要性显著相关。术后第一天矫正不良的钙水平与继续补充骨化三醇和/或钙的需要显著相关。结论:在接受甲状腺癌全甲状腺切除术的患者中,仔细保存甲状旁腺可能会降低永久性补钙的风险,而术后早期血清钙水平下降可能有助于识别需要长期用药的高风险患者。
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来源期刊
Journal of Laryngology and Otology
Journal of Laryngology and Otology 医学-耳鼻喉科学
CiteScore
3.20
自引率
11.80%
发文量
593
审稿时长
3-6 weeks
期刊介绍: The Journal of Laryngology & Otology (JLO) is a leading, monthly journal containing original scientific articles and clinical records in otology, rhinology, laryngology and related specialties. Founded in 1887, JLO is absorbing reading for ENT specialists and trainees. The journal has an international outlook with contributions from around the world, relevant to all specialists in this area regardless of the country in which they practise. JLO contains main articles (original, review and historical), case reports and short reports as well as radiology, pathology or oncology in focus, a selection of abstracts, book reviews, letters to the editor, general notes and calendar, operative surgery techniques, and occasional supplements. It is fully illustrated and has become a definitive reference source in this fast-moving subject area. Published monthly an annual subscription is excellent value for money. Included in the subscription is access to the JLO interactive web site with searchable abstract database of the journal archive back to 1887.
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