A Noncanonical Protein Degradation Pathway That Regulates Germ Cell Maintenance

IF 7.6 1区生物学 Q2 CELL BIOLOGY

Cell Proliferation Pub Date : 2026-10-11 Epub Date: 2026-07-14 DOI:10.1111/cpr.70259

Meng Liu, Xiya Qiu, Wenying Qu, Yue Ma, Mingyuan Bao, Yuxuan Feng, Xiaochu Wang, Tao Zhou, Bo Zheng, Shunyu Hou, Yu Xia, Qingxia Meng

引用次数: 0

Abstract

SENP8 regulates a non-canonical NEDD8-dependent pathway to stabilize STAT1, promote CCL2/CCL5 transcription, and maintain germ cell proliferation and migration.

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调节生殖细胞维持的非规范蛋白降解途径。

SENP8调控非规范的nedd8依赖通路，稳定STAT1，促进CCL2/CCL5转录，维持生殖细胞增殖和迁移。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cell Proliferation 生物-细胞生物学

CiteScore

14.80

自引率

2.40%

发文量

198

审稿时长

1 months

期刊介绍： Cell Proliferation Focus: Devoted to studies into all aspects of cell proliferation and differentiation. Covers normal and abnormal states. Explores control systems and mechanisms at various levels: inter- and intracellular, molecular, and genetic. Investigates modification by and interactions with chemical and physical agents. Includes mathematical modeling and the development of new techniques. Publication Content: Original research papers Invited review articles Book reviews Letters commenting on previously published papers and/or topics of general interest By organizing the information in this manner, readers can quickly grasp the scope, focus, and publication content of Cell Proliferation.