{"title":"Deep Learning-Based Estimation of Distance and Emission Time in Mobile Molecular Communication","authors":"Zhen Cheng;Jianlong Zheng;Yi Luo;Ming Xia;Xinwei Yao;Yongliang Zhang","doi":"10.1109/TMBMC.2026.3701830","DOIUrl":null,"url":null,"abstract":"In molecular communication, estimating the distance between the transmitter and the receiver has a variety of applications at the micro-scale, such as the transmitter or the receiver localization, targeted drug delivery, etc. Existing traditional methods for distance estimation typically rely on mathematical derivations that assume prior knowledge of the emission times of molecules from the transmitters. However, when the emission time is unknown, accurately estimating the distance becomes significantly more challenging and involves higher deduction complexity. In this paper, we propose a deep learning-based approach to simultaneously estimate the distances between multiple transmitters and a receiver and the emission times of molecules. We evaluate the prediction performance of the Transformer model. Simulation results indicate that the Transformer model achieves the highest prediction accuracy for both distances and emission times estimation under given error thresholds, outperforming both the Deep Neural Networks and Informer models, which demonstrates strong prediction ability of the Transformer model.","PeriodicalId":36530,"journal":{"name":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","volume":"12 ","pages":"693-704"},"PeriodicalIF":2.5000,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","FirstCategoryId":"1085","ListUrlMain":"https://ieeexplore.ieee.org/document/11556487/","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/6/9 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"ENGINEERING, ELECTRICAL & ELECTRONIC","Score":null,"Total":0}
引用次数: 0
Abstract
In molecular communication, estimating the distance between the transmitter and the receiver has a variety of applications at the micro-scale, such as the transmitter or the receiver localization, targeted drug delivery, etc. Existing traditional methods for distance estimation typically rely on mathematical derivations that assume prior knowledge of the emission times of molecules from the transmitters. However, when the emission time is unknown, accurately estimating the distance becomes significantly more challenging and involves higher deduction complexity. In this paper, we propose a deep learning-based approach to simultaneously estimate the distances between multiple transmitters and a receiver and the emission times of molecules. We evaluate the prediction performance of the Transformer model. Simulation results indicate that the Transformer model achieves the highest prediction accuracy for both distances and emission times estimation under given error thresholds, outperforming both the Deep Neural Networks and Informer models, which demonstrates strong prediction ability of the Transformer model.
期刊介绍:
As a result of recent advances in MEMS/NEMS and systems biology, as well as the emergence of synthetic bacteria and lab/process-on-a-chip techniques, it is now possible to design chemical “circuits”, custom organisms, micro/nanoscale swarms of devices, and a host of other new systems. This success opens up a new frontier for interdisciplinary communications techniques using chemistry, biology, and other principles that have not been considered in the communications literature. The IEEE Transactions on Molecular, Biological, and Multi-Scale Communications (T-MBMSC) is devoted to the principles, design, and analysis of communication systems that use physics beyond classical electromagnetism. This includes molecular, quantum, and other physical, chemical and biological techniques; as well as new communication techniques at small scales or across multiple scales (e.g., nano to micro to macro; note that strictly nanoscale systems, 1-100 nm, are outside the scope of this journal). Original research articles on one or more of the following topics are within scope: mathematical modeling, information/communication and network theoretic analysis, standardization and industrial applications, and analytical or experimental studies on communication processes or networks in biology. Contributions on related topics may also be considered for publication. Contributions from researchers outside the IEEE’s typical audience are encouraged.