{"title":"Benign <i>struma ovarii</i> mimicking ovarian cancer in an afghan woman: an unusual case report and literature review.","authors":"Maryam Yousefi, Elham Sadat Banimostafavi, Mahdiieh Ghoddoosi","doi":"10.1093/omcr/omag124","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong><i>Struma ovarii</i> is a rare monodermal teratoma composed predominantly of thyroid tissue. While typically benign, its clinical and radiological presentation can be highly deceptive, often mimicking a malignant ovarian tumor.</p><p><strong>Case presentation: </strong>A 52-year-old postmenopausal Afghan woman presented with progressive abdominal distension, pelvic pain, severe ascites, and a complex, highly vascular right adnexal mass. Imaging (ORADS 5) and markedly elevated CA-125 suggested advanced ovarian carcinoma. Despite receiving seven cycles of carboplatin/paclitaxel chemotherapy for presumed primary peritoneal carcinoma, the mass and ascites persisted. Following laparotomy and left salpingo-oophorectomy, histopathology confirmed benign <i>struma ovarii</i> without peritoneal carcinomatosis. Postoperatively, ascites resolved and CA-125 normalized. The patient remained well with no recurrence at 14-month follow-up.</p><p><strong>Conclusion: </strong>This case underscores the critical importance of considering struma ovarii in the differential diagnosis of a complex ovarian mass, even when clinical features and tumor markers strongly suggest malignancy.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2026 7","pages":"omag124"},"PeriodicalIF":0.6000,"publicationDate":"2026-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13356592/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oxford Medical Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/omcr/omag124","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/7/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
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Abstract
Introduction: Struma ovarii is a rare monodermal teratoma composed predominantly of thyroid tissue. While typically benign, its clinical and radiological presentation can be highly deceptive, often mimicking a malignant ovarian tumor.
Case presentation: A 52-year-old postmenopausal Afghan woman presented with progressive abdominal distension, pelvic pain, severe ascites, and a complex, highly vascular right adnexal mass. Imaging (ORADS 5) and markedly elevated CA-125 suggested advanced ovarian carcinoma. Despite receiving seven cycles of carboplatin/paclitaxel chemotherapy for presumed primary peritoneal carcinoma, the mass and ascites persisted. Following laparotomy and left salpingo-oophorectomy, histopathology confirmed benign struma ovarii without peritoneal carcinomatosis. Postoperatively, ascites resolved and CA-125 normalized. The patient remained well with no recurrence at 14-month follow-up.
Conclusion: This case underscores the critical importance of considering struma ovarii in the differential diagnosis of a complex ovarian mass, even when clinical features and tumor markers strongly suggest malignancy.
期刊介绍：
Oxford Medical Case Reports (OMCR) is an open access, peer-reviewed online journal publishing original and educationally valuable case reports that expand the field of medicine. The journal covers all medical specialities including cardiology, rheumatology, nephrology, oncology, neurology, and reproduction, comprising a comprehensive resource for physicians in all fields and at all stages of training. Oxford Medical Case Reports deposits all articles in PubMed Central (PMC). Physicians and researchers can find your work through PubMed , helping you reach the widest possible audience. The journal is also indexed in the Web of Science Core Collection . Oxford Medical Case Reports publishes case reports under the following categories: Allergy Audiovestibular medicine Cardiology and cardiovascular systems Critical care medicine Dermatology Emergency medicine Endocrinology and metabolism Gastroenterology and hepatology Geriatrics and gerontology Haematology Immunology Infectious diseases and tropical medicine Medical disorders in pregnancy Medical ophthalmology Nephrology Neurology Oncology Paediatrics Pain Palliative medicine Pharmacology and pharmacy Psychiatry Radiology, nuclear medicine, and medical imaging Respiratory disorders Rheumatology Sexual and reproductive health Sports Medicine Substance abuse.
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