{"title":"[A case of eosinophilic granulomatosis with polyangiitis presenting with characteristic endoscopic findings in the esophagus and stomach].","authors":"Katsuma Yamauchi, Tomohiro Ueda, Kazuhiro Tsuji, Yasutaka Morimoto, Akiko Shibuya, Tomoyuki Ohno, Tomoki Nakajima, Eiichi Konishi, Norimasa Yoshida, Yoshito Itoh","doi":"10.11405/nisshoshi.123.484","DOIUrl":null,"url":null,"abstract":"<p><p>A woman in her 60s presented with abdominal pain and diarrhea. She had a history of asthma and sinusitis and developed a skin rash and numbness in the lower extremities. Laboratory tests revealed marked eosinophilia, leading to a diagnosis of eosinophilic granulomatosis with polyangiitis (EGPA). Esophagogastroduodenoscopy showed longitudinal erosion in the thoracic esophagus and mucosal color changes ranging from pale to bronze tones in the stomach, extending from the antrum to the angular region. These changes became more evident with insufflation and were not accompanied by inflammatory changes in the mucosa. Given the rarity of reports of esophageal and gastric involvement in EGPA, and to our knowledge, no case has demonstrated insufflation-dependent mucosal changes, this case is noteworthy.</p>","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"123 7","pages":"484-490"},"PeriodicalIF":0.0000,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Japanese Journal of Gastroenterology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.11405/nisshoshi.123.484","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
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Abstract
A woman in her 60s presented with abdominal pain and diarrhea. She had a history of asthma and sinusitis and developed a skin rash and numbness in the lower extremities. Laboratory tests revealed marked eosinophilia, leading to a diagnosis of eosinophilic granulomatosis with polyangiitis (EGPA). Esophagogastroduodenoscopy showed longitudinal erosion in the thoracic esophagus and mucosal color changes ranging from pale to bronze tones in the stomach, extending from the antrum to the angular region. These changes became more evident with insufflation and were not accompanied by inflammatory changes in the mucosa. Given the rarity of reports of esophageal and gastric involvement in EGPA, and to our knowledge, no case has demonstrated insufflation-dependent mucosal changes, this case is noteworthy.
期刊介绍：
The Journal of Gastroenterology, which is the official publication of the Japanese Society of Gastroenterology, publishes Original Articles (Alimentary Tract/Liver, Pancreas, and Biliary Tract), Review Articles, Letters to the Editors and other articles on all aspects of the field of gastroenterology. Significant contributions relating to basic research, theory, and practice are welcomed. These publications are designed to disseminate knowledge in this field to a worldwide audience, and accordingly, its editorial board has an international membership.
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