Nausea and vomiting of pregnancy in relation to fear of childbirth: Evidence from a Finnish cohort

IF 3.5 2区医学 Q1 OBSTETRICS & GYNECOLOGY

Acta Obstetricia et Gynecologica Scandinavica Pub Date : 2026-09-15 Epub Date: 2026-07-09 DOI:10.1111/aogs.70307

Anna Murto, Linda Laitinen, Eeva Terävä-Utti, Miina Nurmi, Mari Koivisto, Päivi Polo-Kantola

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引用次数: 0

Abstract

Introduction

Nausea and vomiting of pregnancy (NVP) is a common disorder affecting most pregnant women. Previous studies have suggested associations between NVP and psychological pregnancy complications, whereas only a limited number of studies have explored a possible association with fear of childbirth (FOC). Shared biological underlying factors have been proposed, but the precise mechanisms remain poorly understood. The objective of our study was to explore the relationship between NVP and FOC.

Material and Methods

Pregnant women (n = 2411) were recruited from maternity health care clinics in the Turku area, Finland. The severity of NVP was evaluated with the Pregnancy-Unique Quantification of Emesis (PUQE) questionnaire, and the women were categorized into two groups: the no/mild NVP group (PUQE points 3–6, n = 963) and the moderate/severe NVP group (PUQE points 7–15, n = 1366). Data on FOC (International Statistical Classification of Diseases, 10th Revision [ICD-10] code O99.80) and maternal characteristics (age, body mass index, parity, marital status, employment status, and smoking) were drawn from the Finnish Medical Birth Register. The association between NVP and FOC was evaluated using logistic regression adjusted for maternal characteristics.

Results

The data of 2329 women were eligible for the analysis. Compared with the women in the no/mild NVP group, those in the moderate/severe NVP group were more likely to suffer from FOC (OR 1.69, 95% CI 1.11–2.58, p = 0.015). The difference between the groups remained after adjustment for maternal background factors (aOR 1.72, 95% CI 1.09–2.71, p = 0.019).

Conclusions

We showed an association between more severe NVP and FOC. The evidence from our study implies that, beyond the physical manifestation, NVP may contribute to psychological distress and influence women's perception of childbirth. These findings highlight the importance of also addressing the psychological aspects of NVP in clinical care.

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查看原文本刊更多论文

妊娠期恶心和呕吐与分娩恐惧的关系：来自芬兰队列的证据。

妊娠恶心呕吐（NVP）是影响大多数孕妇的常见疾病。先前的研究表明NVP与心理妊娠并发症之间存在关联，而只有有限数量的研究探讨了NVP与分娩恐惧（FOC）的可能关联。已经提出了共同的生物学潜在因素，但精确的机制仍然知之甚少。本研究旨在探讨NVP与FOC之间的关系。材料和方法：从芬兰图尔库地区的产妇保健诊所招募孕妇（n = 2411）。采用妊娠独特呕吐量化（PUQE）问卷评估NVP的严重程度，并将妇女分为两组：无/轻度NVP组（PUQE分3-6分，n = 963）和中/重度NVP组（PUQE分7-15分，n = 1366）。关于FOC（国际疾病统计分类，第十次修订[ICD-10]代码O99.80）和产妇特征（年龄、体重指数、胎次、婚姻状况、就业状况和吸烟）的数据取自芬兰医疗出生登记册。NVP和FOC之间的关系使用经母体特征调整的逻辑回归进行评估。结果：2329名妇女的资料符合分析条件。与无/轻度NVP组相比，中度/重度NVP组更容易发生FOC （OR 1.69, 95% CI 1.11-2.58, p = 0.015）。在调整母体背景因素后，两组间的差异仍然存在（aOR 1.72, 95% CI 1.09-2.71, p = 0.019）。结论：我们发现更严重的NVP和FOC之间存在关联。本研究的证据表明，除了身体表现外，NVP还可能导致心理困扰并影响妇女对分娩的看法。这些发现强调了在临床护理中处理NVP的心理方面的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta Obstetricia et Gynecologica Scandinavica 医学-妇产科学

CiteScore

8.00

自引率

4.70%

发文量

180

审稿时长

3-6 weeks

期刊介绍： Published monthly, Acta Obstetricia et Gynecologica Scandinavica is an international journal dedicated to providing the very latest information on the results of both clinical, basic and translational research work related to all aspects of women’s health from around the globe. The journal regularly publishes commentaries, reviews, and original articles on a wide variety of topics including: gynecology, pregnancy, birth, female urology, gynecologic oncology, fertility and reproductive biology.