Combining electroacupuncture and transcutaneous electrical acupoint stimulation for psychiatric disorders in women victims of domestic violence: An assessor-blinded, randomised controlled trial.

IF 9.9 3区医学 Q1 PSYCHIATRY

General Psychiatry Pub Date : 2026-08-01 Epub Date: 2026-07-07 DOI:10.1002/gps3.70035

Sichang Yang, Wai Chun Mok, Denise Shuk Ting Cheung, Agnes Tiwari, Calvin Pak Wing Cheng, Haiyong Chen, Zongshi Qin, Mei Yan Chan, Xiaoru Hu, Kam Chi Yu, Pui Yan Chan, Wenqi Li, Sheng-Nan Liu, Min-Qing Gu, Xinjing Yang, Doris Lee, Sai Ho Sin, Zhang-Jin Zhang

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引用次数: 0

Abstract

Background: Women victims of domestic violence often present with psychiatric disorders and may benefit from nonpharmacological interventions. Acupoint stimulation therapy may be an effective approach.

Aims: To examine whether a combination of electroacupuncture (EA) and transcutaneous electrical acupoint stimulation (TEAS) can alleviate depression, post-traumatic stress disorder (PTSD) and insomnia in women victims of domestic violence.

Methods: An assessor-blinded randomised controlled trial was conducted in Hong Kong, China, with 110 Chinese women with major depressive disorder who had experienced domestic violence and were randomly assigned to care as usual (CAU) alone or combined with EA + TEAS (n = 55 per group) for 12 weeks, two clinic-based EA sessions and three home-based TEAS sessions per week. The primary outcome was baseline-to-endpoint change in the Beck Depression Inventory-II (BDI-II). Secondary outcomes included the 17-item Hamilton Depression Rating Scale, 10-item Perceived Stress Scale, PTSD Check List-Civilian Version, Insomnia Severity Index and the 12-item Short Form Survey for health-related quality of life.

Results: Of the 110 participants (n = 55 each group), 91.8% (101/110) completed the study. At 12 weeks, the EA + TEAS group showed a significantly greater reduction in BDI-II score than that of the CAU group (mean difference = -10.9; 95% confidence interval -16.5 to -5.4; t = -3.9; p < 0.001), exceeding the minimal clinically important difference (5 points). The superiority of EA + TEAS was also observed across secondary measures, including depression, PTSD, perceived stress, insomnia and quality of life. The EA + TEAS group had significantly higher rates of clinical response (49.1% vs. 18.2%, χ ² = 11.770, p < 0.001) and remission (38.2% vs. 12.7%, χ ² = 9.390, p = 0.002) at endpoint than those of the CAU group. All treatment-related adverse events were mild.

Conclusions: The addition of EA + TEAS produced substantially greater improvements in depression and other psychiatric symptoms. EA + TEAS may serve as an effective intervention for women victims of domestic violence.

Trial registration: This trial was registered on www.clinicaltrials.gov (NCT05102253).

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结合电针和经皮穴位电刺激治疗家庭暴力女性受害者的精神障碍：一项评估盲、随机对照试验

背景：家庭暴力的妇女受害者通常表现为精神障碍，可能从非药物干预中受益。穴位刺激疗法可能是有效的治疗方法。目的：探讨电针（EA）联合经皮穴位电刺激（TEAS）是否能缓解家庭暴力女性受害者的抑郁、创伤后应激障碍（PTSD）和失眠。方法：在中国香港进行了一项评估盲随机对照试验，110名经历过家庭暴力的中国重度抑郁症女性被随机分配到单独的常规护理（CAU）或联合EA + TEAS（每组55人），为期12周，每周两次临床EA治疗和三次家庭tea治疗。主要终点是贝克抑郁量表ii （BDI-II）的基线至终点变化。次要结果包括17项汉密尔顿抑郁评定量表、10项感知压力量表、创伤后应激障碍平民版检查表、失眠严重程度指数和12项健康相关生活质量简短调查。结果：在110名参与者中（每组55人），91.8%（101/110）完成了研究。12周时，EA + TEAS组终点BDI-II评分下降幅度明显大于CAU组（平均差值= -10.9；95%可信区间为-16.5 ~ -5.4;t = -3.9; p χ 2 = 11.770, p χ 2 = 9.390, p = 0.002）。所有治疗相关不良事件均为轻度。结论：EA + TEAS的加入对抑郁和其他精神症状产生了更大的改善。EA + TEAS可作为对家庭暴力受害妇女的有效干预。试验注册：该试验在www.clinicaltrials.gov （NCT05102253）上注册。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

General Psychiatry 医学-精神病学

CiteScore

21.90

自引率

2.50%

发文量

848

期刊介绍： General Psychiatry (GPSYCH), an open-access journal established in 1959, has been a pioneer in disseminating leading psychiatry research. Addressing a global audience of psychiatrists and mental health professionals, the journal covers diverse topics and publishes original research, systematic reviews, meta-analyses, forums on topical issues, case reports, research methods in psychiatry, and a distinctive section on 'Biostatistics in Psychiatry'. The scope includes original articles on basic research, clinical research, community-based studies, and ecological studies, encompassing a broad spectrum of psychiatric interests.