Dustine Reich, Cynthia M Magro, Kira Minkis, Shari R Lipner
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引用次数: 0
Abstract
Introduction: Nail squamous cell carcinomas (SCCs) in skin of color (SoC) patients are exceedingly rare, with only 29 cases previously reported.
Case presentation: We describe the case of a female Fitzpatrick skin-type V patient who presented with a 3-year history of a hyperpigmented plaque involving the proximal nail fold of her right thumbnail. The patient reported a positive Pap smear for human papillomavirus (HPV) 16 and 18 seventeen years ago and had not received the HPV vaccine. Biopsy showed SCC positive for high-risk HPV, and the patient underwent Mohs surgery.
Conclusion: This case adds to only five prior reports of female SoC patients with nail SCC and emphasizes the importance of considering nail SCC in the differential diagnosis of a hyperpigmented nail fold, especially with a history of HPV.
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