Si-Miao-Yong-An Decoction ameliorates Deep vein thrombosis by suppressing NAT10-mediated ac4C modification of HMOX1 mRNA

IF 11.3 1区 医学 Q1 CHEMISTRY, MEDICINAL
Yunhong Zhang, Zhen Zhang, Xinkui Liu, Yurou Wang, Nannan Fan, Xiaoyan Yu, Qiaoqiao Han, Chu Chu, Wenhua Li, Feifei Shi, Bin Wang, Xia Li
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引用次数: 0
四妙永安汤通过抑制nat10介导的HMOX1 mRNA的ac4C修饰改善深静脉血栓形成
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来源期刊
Phytomedicine
Phytomedicine 医学-药学
CiteScore
10.30
自引率
5.10%
发文量
670
审稿时长
91 days
期刊介绍: Phytomedicine is a therapy-oriented journal that publishes innovative studies on the efficacy, safety, quality, and mechanisms of action of specified plant extracts, phytopharmaceuticals, and their isolated constituents. This includes clinical, pharmacological, pharmacokinetic, and toxicological studies of herbal medicinal products, preparations, and purified compounds with defined and consistent quality, ensuring reproducible pharmacological activity. Founded in 1994, Phytomedicine aims to focus and stimulate research in this field and establish internationally accepted scientific standards for pharmacological studies, proof of clinical efficacy, and safety of phytomedicines.
文献相关原料
原料信息
原料厂家
1
anti-ac4C antibody
2
anti-GAPDH antibody
3
anti-HMOX1 antibody
4
anti-NAT10 antibody
5
Halo-C18 column
6
SD rats
7
C57BL/6J mice
8
C57BL/6J mice
9
SD rats
10
C166 cells
11
HUVECs
12
CCK8 solution
13
scanning confocal microscope
14
TRIzol Reagent
15
Endothelial-specific NAT10 knockout mice
16
BIACORE T200
17
carboxymethyl 7 sensor chip
18
FerroOrange
19
AAV-HMOX1
20
GV314 adenoviral system
21
Fibroblast Isolation Kit
22
NAT10 protein
23
microplate reader
24
Tanon 5200 chemiluminescent imaging system
25
Mouse Vascular Endothelial Cell Isolation Kit
26
Orbitrap Exploris 120 mass spectrometer
27
Vanquish UHPLC system
28
Small Animal Ultrasound Imaging System
29
HRP-conjugated anti-rabbit IgG secondary antibody
30
ferrous ion content assay kit
31
LPO Content Assay Kit
32
MDA Content Assay Kit
33
Reduced GSH Content Assay Kit
34
22
calycosin
20575-57-9
¥125.00-¥12432.00
35
22
kaempferol
520-18-3
¥25.00-¥19052.00
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