Host membranes provide hidden gateways for 'accidental pathogens'.

IF 18.7 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Trends in Microbiology Pub Date : 2026-10-01 Epub Date: 2026-07-06 DOI:10.1016/j.tim.2026.06.003

Mathieu Coureuil, Stefano Marullo

引用次数: 0

Abstract

Human infection often results from accidental host-pathogen interactions rather than from evolutionary microbial adaptation. In this forum, we highlight how intrinsic host plasma membrane properties-deformation, curvature sensing, receptor enrichment, and membrane reservoirs-support diverse bacterial processes of adhesion and entry.

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宿主膜为“偶然病原体”提供了隐藏的通道。

人类感染通常是偶然的宿主-病原体相互作用而不是进化微生物适应的结果。在这个论坛上，我们强调宿主质膜的固有特性——变形、曲率传感、受体富集和膜库——如何支持各种细菌的粘附和进入过程。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Trends in Microbiology 生物-生化与分子生物学

CiteScore

25.30

自引率

0.60%

发文量

193

审稿时长

6-12 weeks

期刊介绍： Trends in Microbiology serves as a comprehensive, multidisciplinary forum for discussing various aspects of microbiology, spanning cell biology, immunology, genetics, evolution, virology, bacteriology, protozoology, and mycology. In the rapidly evolving field of microbiology, technological advancements, especially in genome sequencing, impact prokaryote biology from pathogens to extremophiles, influencing developments in drugs, vaccines, and industrial enzyme research.