Effects of OsteoStrong vs. dynamic multicomponent exercise on physical function in older women in the BONEMORE randomized controlled trial

IF 4.7 3区 医学 Q2 GERIATRICS & GERONTOLOGY
Aging Clinical and Experimental Research Pub Date : 2026-07-05 Epub Date: 2026-07-30 DOI:10.1007/s40520-026-03421-4
Peter W.S. Lindberg, Hans Ranch Lundin, Eva Andersson, Ann-Charlotte Grahn Kronhed, Eva Toth-Pal, Maria Sääf, Christina Kaijser Alin, Helena Salminen
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Abstract

Background

Limited research exists on the effects of OsteoStrong on physical function in older women.

Aim

This randomized controlled trial aimed to evaluate and compare the effects of OsteoStrong (OS) and dynamic multicomponent exercise (DME) on functional outcomes in older women with osteopenia or osteoporosis.

Methods

A total of 194 women aged 65–79 years with a T-score of ≤–1.0 at the hip and/or spine were randomized to nine months of either OS (once weekly, 20 min) or DME (twice weekly, 60 min). Outcomes included measures of muscle strength (hand grip and back strength), back and trunk endurance, mobility (sit-to-stand tests, gait speed, Timed Up and Go), and balance (one-leg standing time, tandem standing, tandem walking). Measurements were conducted at baseline and again at nine months.

Results

Both OS and DME showed significant improvements in grip strength, back strength, isometric trunk flexion endurance, gait speed 30 m (m/sec), 5 sit-to-stand (sec) and 50 sit-to-stand speed (n/sec). DME resulted in greater improvements in gait speed 30 m (m/sec) (+ 7.1% vs. +3.2%, p = 0.001), isometric trunk extension (+ 27.6% vs. +4.4%, p = 0.007), and one-leg standing balance (right leg: +13.1% vs. -2.1%, p = 0.001; left leg:+13.3% vs. -2.4%, p = 0.001) compared to OS, while no significant between-group differences were observed for the remaining outcomes.

Conclusion

These findings suggest that while both OS and DME improve physical function in older women with osteopenia or osteoporosis, DME provides superior benefits in gait speed, back muscle endurance, and balance. These findings should be interpreted with caution, as they are based on secondary outcomes.

在BONEMORE随机对照试验中,骨强与动态多组分运动对老年妇女身体功能的影响。
背景:关于OsteoStrong对老年女性身体功能影响的研究有限。目的:本随机对照试验旨在评估和比较OsteoStrong (OS)和动态多组分运动(DME)对骨质减少或骨质疏松症老年妇女功能结局的影响。方法:194名年龄65-79岁,髋部和/或脊柱t评分≤-1.0的女性随机分为9个月的OS组(每周一次,20分钟)或DME组(每周一次,60分钟)。结果包括肌肉力量(握力和背部力量)、背部和躯干耐力、机动性(坐立测试、步态速度、定时起身和行走)和平衡(单腿站立时间、串联站立、串联行走)的测量。在基线和9个月时再次进行测量。结果:OS和DME在握力、背部力量、躯干等距屈曲耐力、30 m (m/sec)、5坐立(sec)和50坐立速度(n/sec)方面均有显著改善,组间无显著差异。与OS相比,DME在30米的步速(+ 7.1% vs. +3.2%, p = 0.001)、躯干等距伸展(+ 27.6% vs. +4.4%, p = 0.007)和单腿站立平衡(右腿:+13.1% vs. -2.1%, p = 0.001;左腿:+13.3% vs. -2.4%, p = 0.001)方面的改善更大。结论:这些发现表明,虽然OS和DME都能改善骨质疏松症或骨质疏松症老年妇女的身体功能,但DME在步态速度、背部肌肉耐力和平衡方面具有更大的益处。这些发现应谨慎解释,因为它们是基于次要结果。
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来源期刊
CiteScore
7.90
自引率
5.00%
发文量
283
审稿时长
1 months
期刊介绍: Aging clinical and experimental research offers a multidisciplinary forum on the progressing field of gerontology and geriatrics. The areas covered by the journal include: biogerontology, neurosciences, epidemiology, clinical gerontology and geriatric assessment, social, economical and behavioral gerontology. “Aging clinical and experimental research” appears bimonthly and publishes review articles, original papers and case reports.
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