{"title":"Methodological and Statistical Confounding in Comparing Patient-Reported Outcomes Between Cardioversion and Ablation for Atrial Fibrillation","authors":"Faizan Raza","doi":"10.1002/clc.70407","DOIUrl":null,"url":null,"abstract":"<p>I read with great interest the article by Oren et al. [<span>1</span>] evaluating patient-reported outcome measures (PROMs) following elective electrical cardioversion versus catheter ablation for atrial fibrillation. While I commend the authors for investigating clinically relevant endpoints like sleep, health, and anxiety, several structural inconsistencies and methodological confounding factors limit the finality of their conclusions.</p><p>To enhance future comparison of rhythm control strategies, the investigator should implement a minimum of 6−12 months follow-up timeline to outlast the blanking period. Furthermore, utilizing ANCOVA modeling is essential to properly account for pre-existing baseline psychometric variations.</p><p>Data sharing is not applicable to this article as no data sets were generated or analyzed during the current study.</p>","PeriodicalId":10201,"journal":{"name":"Clinical Cardiology","volume":"49 7","pages":""},"PeriodicalIF":2.8000,"publicationDate":"2026-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/clc.70407","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Cardiology","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/clc.70407","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0
Abstract
I read with great interest the article by Oren et al. [1] evaluating patient-reported outcome measures (PROMs) following elective electrical cardioversion versus catheter ablation for atrial fibrillation. While I commend the authors for investigating clinically relevant endpoints like sleep, health, and anxiety, several structural inconsistencies and methodological confounding factors limit the finality of their conclusions.
To enhance future comparison of rhythm control strategies, the investigator should implement a minimum of 6−12 months follow-up timeline to outlast the blanking period. Furthermore, utilizing ANCOVA modeling is essential to properly account for pre-existing baseline psychometric variations.
Data sharing is not applicable to this article as no data sets were generated or analyzed during the current study.
期刊介绍：
Clinical Cardiology provides a fully Gold Open Access forum for the publication of original clinical research, as well as brief reviews of diagnostic and therapeutic issues in cardiovascular medicine and cardiovascular surgery.
The journal includes Clinical Investigations, Reviews, free standing editorials and commentaries, and bonus online-only content.
The journal also publishes supplements, Expert Panel Discussions, sponsored clinical Reviews, Trial Designs, and Quality and Outcomes.
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