{"title":"Five Issues of Artificial Intelligence in Science: Sailing the Ship of Theseus","authors":"S. Thomas Carmichael MD, PhD","doi":"10.1002/ana.78298","DOIUrl":null,"url":null,"abstract":"<p>Artificial intelligence (AI) is becoming part of the working infrastructure of academic medicine. Because grants convert scientific ideas into protected time, infrastructure, and institutional priority, they provide a revealing test case for AI's effects on biomedicine. Five issues are emerging: language, agency, review, doership, and identity. AI can polish weak proposals, shift the origin of ideas, align proposal and review language around fundability, and create feasibility theater, projects that sound executable, but exceed a laboratory's capacity. The challenge is to keep AI anchored to lived expertise, the experience of failure, and the formative work by which faculty become scientists. ANN NEUROL 2026;100:453–457</p>","PeriodicalId":127,"journal":{"name":"Annals of Neurology","volume":"100 3","pages":"453-457"},"PeriodicalIF":7.5000,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ana.78298","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of Neurology","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/ana.78298","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/7/2 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Artificial intelligence (AI) is becoming part of the working infrastructure of academic medicine. Because grants convert scientific ideas into protected time, infrastructure, and institutional priority, they provide a revealing test case for AI's effects on biomedicine. Five issues are emerging: language, agency, review, doership, and identity. AI can polish weak proposals, shift the origin of ideas, align proposal and review language around fundability, and create feasibility theater, projects that sound executable, but exceed a laboratory's capacity. The challenge is to keep AI anchored to lived expertise, the experience of failure, and the formative work by which faculty become scientists. ANN NEUROL 2026;100:453–457
期刊介绍:
Annals of Neurology publishes original articles with potential for high impact in understanding the pathogenesis, clinical and laboratory features, diagnosis, treatment, outcomes and science underlying diseases of the human nervous system. Articles should ideally be of broad interest to the academic neurological community rather than solely to subspecialists in a particular field. Studies involving experimental model system, including those in cell and organ cultures and animals, of direct translational relevance to the understanding of neurological disease are also encouraged.