Impact of a Structured Caesarean Reduction Strategy on Perinatal Outcomes: A Retrospective Ecological Time‐Trend Study

Stefania Fieni, Giovanni Morganelli, Gabriella Maria Celora, Biancamaria Mastrandrea, Tullio Ghi
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Abstract

Objective To evaluate the long‐term impact of a structured, multidisciplinary CS reduction strategy in a high‐complexity Italian hospital. Design Retrospective ecological time‐trend study. Setting Tertiary obstetric care Italian centre. Sample 28 577 deliveries, ≥ 22 weeks' gestation, from 2014 to 2024 were analysed. Methods In 2014, a multifaceted improvement program including standardised protocols, continuous staff training, Robson Ten‐Group Classification audits, and tailored intrapartum care (revised dystocia criteria, updated induction methods, intrapartum ultrasound, dedicated VBAC clinic, and physiology‐based CTG interpretation) was introduced. Main Outcome Measure Temporal trend in CS rate, maternal morbidity (postpartum haemorrhage > 1000 mL, obstetric anal sphincter injuries, hysterectomy) and neonatal morbidity (cord pH < 7.0, resuscitation, therapeutic hypothermia). Temporal trends were assessed using segmented regression. Results Segmented regression analysis of CS rates identified 2016 as a breakpoint. Prior to 2016, the annual change in CS rate was not significant (−0.24 percentage points per year; p = 0.75), whereas after 2016 a significant downward trend was observed (−1.64 percentage points per year; p < 0.001). Conversely, VBAC rates showed a significant increasing trend over time, while uterine rupture rates remained consistently below 0.3% throughout the study period. Maternal outcomes were overall stable, although a modest increase in postpartum haemorrhage was observed. Neonatal outcomes did not show significant changes over time, including the rate of arterial cord pH < 7.0 at birth. Conclusions The implementation of a structured, multifaceted strategy aimed at containing CS rates was associated with a significant change in their temporal trend, with a sustained post‐2016 decline identified by segmented regression analysis. This trend was not associated with clinically significant detrimental effects on maternal or neonatal outcomes.
结构性剖宫产术对围产期结局的影响:一项回顾性生态学时间趋势研究
目的评价在意大利一家高度复杂的医院采用结构化、多学科的CS减少策略的长期影响。设计回顾性生态时间趋势研究。设置三级产科护理意大利中心。对2014 ~ 2024年妊娠≥22周的28577例分娩进行分析。方法2014年,引入了一项多方面的改进计划,包括标准化方案、持续的员工培训、Robson十组分类审计和量身定制的产时护理(修订难产标准、更新诱导方法、产时超声、专用VBAC诊所和基于生理的CTG解释)。主要观察指标:CS率、产妇发病率(产后出血1000 mL、产科肛门括约肌损伤、子宫切除术)和新生儿发病率(脐带pH 7.0、复苏、治疗性低温)的时间趋势。使用分段回归评估时间趋势。结果分割回归分析将2016年确定为断点。在2016年之前,CS率的年变化不显著(- 0.24个百分点/年,p = 0.75),而在2016年之后,CS率呈显著下降趋势(- 1.64个百分点/年,p < 0.001)。相反,随着时间的推移,VBAC率呈显著上升趋势,而子宫破裂率在整个研究期间始终保持在0.3%以下。尽管观察到产后出血的适度增加,但产妇结局总体稳定。新生儿结局没有显示出随时间的显著变化,包括出生时动脉脐带pH 7.0的比率。通过分段回归分析,研究人员发现,实施一项旨在控制自杀率的结构化、多角度策略与自杀率的时间趋势发生了显著变化,并在2016年后持续下降。这一趋势与临床上对产妇或新生儿结局的显著不利影响无关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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