Congenital cytomegalovirus: Screening strategies and diagnostic challenges

IF 3.2 3区医学 Q1 OBSTETRICS & GYNECOLOGY

Seminars in perinatology Pub Date : 2026-09-01 Epub Date: 2026-07-02 DOI:10.1016/j.semperi.2026.152278

Karen Ravin, Terri Stillwell

引用次数: 0

Abstract

Congenital cytomegalovirus (cCMV) infection is the most common congenital infection worldwide and a leading cause of sensorineural hearing loss (SNHL). Most newborns with cCMV will be asymptomatic at birth; however, a subset will go on to develop disease, including SNHL and neurodevelopmental problems, later in life. Given this, advocacy for newborn cCMV screening is growing. Targeted versus universal screening remains a hotly debated topic. This review will assess current diagnostic and screening modalities and explore unanswered questions.

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先天性巨细胞病毒：筛查策略和诊断挑战。

先天性巨细胞病毒（cCMV）感染是世界范围内最常见的先天性感染，也是引起感音神经性听力损失（SNHL）的主要原因。大多数患有cCMV的新生儿在出生时无症状；然而，一部分人会在以后的生活中继续发展疾病，包括SNHL和神经发育问题。鉴于此，倡导新生儿cCMV筛查的呼声越来越高。靶向筛查与普遍筛查仍然是一个激烈争论的话题。本综述将评估当前的诊断和筛查方式，并探讨未解决的问题。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Seminars in perinatology 医学-妇产科学

CiteScore

5.80

自引率

2.90%

发文量

审稿时长

6-12 weeks

期刊介绍： The purpose of each issue of Seminars in Perinatology is to provide authoritative and comprehensive reviews of a single topic of interest to professionals who care for the mother, the fetus, and the newborn. The journal''s readership includes perinatologists, obstetricians, pediatricians, epidemiologists, students in these fields, and others. Each issue offers a comprehensive review of an individual topic, with emphasis on new developments that will have a direct impact on their practice.