Evaluation of the BT-50 Automatic Quality Control Unit on the XN9000 Hematology Analyzer

IF 2.2 4区医学 Q3 HEMATOLOGY

International Journal of Laboratory Hematology Pub Date : 2026-09-09 Epub Date: 2026-06-29 DOI:10.1111/ijlh.70184

Congyu Zou, Yan Wei, Yuyin Liu, Xiaoqian Zeng

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引用次数: 0

Abstract

Objective

This study aims to explore the application of BT50-based automatic quality control in the XN9000 hematology analyzer line, comparing its benefits and limitations with manual QC procedures, and to identify potential improvements, thereby providing a reference for the development of automated QC in clinical laboratories.

Methods

Both manual and automatic QC procedures were performed for blood cell analysis. Manual QC data (January 1, 2024, to July 31, 2024) and automatic QC data (August 1, 2024, to February 28, 2025) were collected from the Department of Clinical Laboratory, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology. SPSS 18.0 software was used for the statistical analysis. The parameters analyzed included the coefficient of variation (CV), daily QC completion time, first sample review time, and staff workload.

Results

(1) Compared to manual QC, no statistically significant differences were observed in the CV values of any parameters between the two methods (Mann–Whitney U test, p > 0.05 for all). (2) The median completion time for automatic QC was 42 min earlier than that for manual QC, with automatic QC finishing at 07:48:47 (IQR: 07:47:55, 07:48:46) and manual QC finishing at 08:30:34 (IQR: 08:24:17, 08:37:32). (3) With a daily work start time of 08:00, the median first sample review time was advanced by 20 min under automatic QC, with manual QC reviewed at 08:48:00 (IQR: 08:36:00, 08:50:30) and automatic QC reviewed at 08:28:00 (IQR: 08:21:30, 09:07:30). (4) The automatic QC system significantly reduced the number of manual steps, including those for storage, rewarming, mixing, and post-analysis storage.

Conclusion

Implementing the automatic QC system facilitates earlier report review, reduces workload, enhances operational efficiency, and maintains CV values within acceptable laboratory standards.

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BT-50自动质量控制单元在XN9000血液学分析仪上的评价。

目的：探讨基于bt50的自动质量控制在XN9000血液学分析仪生产线上的应用，比较其与人工QC程序的优点和局限性，并找出改进的地方，为临床实验室自动化质量控制的发展提供参考。方法：采用手工和自动QC方法进行血细胞分析。人工QC数据（2024年1月1日至2024年7月31日）和自动QC数据（2024年8月1日至2025年2月28日）采集于华中科技大学同济医学院协和医院检验科。采用SPSS 18.0软件进行统计分析。分析的参数包括变异系数（CV）、每日QC完成时间、首样审核时间和员工工作量。结果：(1)与人工QC相比，两种方法各参数CV值无统计学差异（Mann-Whitney U检验，p < 0.05）。(2)自动QC完成时间中位数比人工QC早42 min，自动QC完成时间为07:48:47 (IQR: 07:47:55, 07:48:46)，人工QC完成时间为08:30:34 （IQR: 08:24:17, 08:37:32）。(3)每日工作开始时间为08:00，自动QC下首样审核时间中位数提前20分钟，手动QC审核时间为08:48:00 (IQR: 08:36:00, 08:50:30)，自动QC审核时间为08:28:00 （IQR: 08:21:30, 09:07:30）。(4)自动QC系统大大减少了人工步骤，包括储存、再温、混合和分析后储存。结论：实施自动QC系统有助于早期报告审核，减少工作量，提高操作效率，并将CV值保持在可接受的实验室标准范围内。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Laboratory Hematology 医学-血液学

CiteScore

4.50

自引率

6.70%

发文量

211

审稿时长

6-12 weeks

期刊介绍： The International Journal of Laboratory Hematology provides a forum for the communication of new developments, research topics and the practice of laboratory haematology. The journal publishes invited reviews, full length original articles, and correspondence. The International Journal of Laboratory Hematology is the official journal of the International Society for Laboratory Hematology, which addresses the following sub-disciplines: cellular analysis, flow cytometry, haemostasis and thrombosis, molecular diagnostics, haematology informatics, haemoglobinopathies, point of care testing, standards and guidelines. The journal was launched in 2006 as the successor to Clinical and Laboratory Hematology, which was first published in 1979. An active and positive editorial policy ensures that work of a high scientific standard is reported, in order to bridge the gap between practical and academic aspects of laboratory haematology.