Infection prevention and control of Candida auris in pediatric settings.

Thomas S Murray, Hana Hakim, Christelle Ilboudo, Lynn Ramírez-Ávila, Jana Shaw, Terri Stillwell, Patricia Budo, Bernard Ebruke, Noa Fleiss, Amanda Green, Matthew Linam, Roshni Mathew, April McDougal, Natalie Neu, Zoi Dorothea Pana, Karen Ravin, Ayelet Rosenthal, Jane D Siegel, Katlyn Steimel, Amy Valencia, Carol Vance, Lars F Westblade, Lisa Saiman
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Abstract

Background: Candida auris (also referred to as Candidozyma auris) is an emerging multidrug-resistant fungal pathogen associated with high morbidity and mortality. Existing infection prevention and control (IPC) guidance has largely focused on adult populations, with limited recommendations for pediatric healthcare and non-healthcare settings.

Methods: The Society for Healthcare Epidemiology of America (SHEA) convened a multidisciplinary expert panel to develop IPC recommendations for C. auris. The panel developed recommendations using a structured, iterative Delphi consensus process with rounds of discussion, refinement, and anonymous electronic voting with predefined consensus thresholds. Panelists reviewed relevant peer-reviewed and gray literature integrated with expert judgment and practical considerations. Preambles and remarks provide additional context and guidance.

Results: This consensus statement provides recommendations for prevention of C. auris in pediatric acute care settings, non-acute healthcare settings, and non-healthcare congregate settings. Recommendations incorporate pediatric risk factors and care and address screening practices, isolation precautions, caregiver-infant/child dyad considerations, room placement and rooming in, breastfeeding and skin-to-skin practices, visitation, use of shared spaces, environmental cleaning and disinfection, and management of medical and non-medical equipment, including toys. Recommendations emphasize coordination with local infection prevention and public health partners.

Conclusions: This SHEA consensus statement addresses gaps in pediatric-specific IPC guidance for C. auris. The recommendations provide a practical framework to support prevention of transmission within the context of pediatric clinical, developmental, and family-centered care.

小儿耳念珠菌感染的预防和控制。
背景:耳念珠菌(也称为耳念珠菌)是一种新兴的多药耐药真菌病原体,具有很高的发病率和死亡率。现有的感染预防和控制(IPC)指南主要侧重于成人人群,对儿科卫生保健和非卫生保健机构的建议有限。方法:美国卫生保健流行病学学会(SHEA)召集了一个多学科专家小组,制定auris的IPC建议。专家组采用结构化的、迭代的德尔菲共识过程,通过预先定义的共识阈值进行轮次讨论、细化和匿名电子投票,提出了建议。小组成员回顾了相关的同行评审和灰色文献,结合了专家判断和实际考虑。序言和评注提供了更多的背景和指导。结果:这一共识声明为儿科急性护理环境、非急性医疗保健环境和非医疗保健聚集环境中预防auris提供了建议。建议将儿科风险因素和护理纳入其中,并涉及筛查做法、隔离预防措施、照顾者-婴儿/儿童二元关系的考虑、房间布置和分房、母乳喂养和皮肤接触做法、探视、共用空间的使用、环境清洁和消毒以及医疗和非医疗设备(包括玩具)的管理。建议强调与当地感染预防和公共卫生伙伴的协调。结论:本SHEA共识声明解决了针对auris的儿科特异性IPC指南中的空白。这些建议提供了一个实用的框架,以支持在儿科临床、发育和以家庭为中心的护理背景下预防传播。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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