A pair of epimeric lignan glycosides from Selaginella tamariscina.

IF 1.6 3区 医学 Q3 CHEMISTRY, APPLIED
Shuai-Cong Ni, Hai-Xiao-Lin-Mo Ma, A-Ji Diri, Yuan Liu, Xin-Jia Yan, Jing Wen
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引用次数: 0

Abstract

To explore the chemical constituents of Selaginella tamariscina and their effects on cancer cells, this study employed multiple chromatographic techniques including polyamide, silica gel, and semi-preparative High-performance liquid chromatography for compound isolation. The structures of the compounds were elucidated based on physicochemical properties and spectroscopic data. A pair of epimeric lignan glycosides, 7'R-tamariscinol U 4-O-β-d-glucopyranoside (1), 7'S-tamariscinol U 4-O-β-d-glucopyranoside (2) were obtained, along with two known compounds 3,5,7-trimethoxyflavone-4'-O-β-d-glucopyranoside (3) and selapeptin B (4). 1 and 2 are new, while the spectral data of 3 and 4 in methanol-d4 are reported for the first time.

来自卷柏的一对外聚木脂素苷。
为了探究卷柏的化学成分及其对肿瘤细胞的作用,本研究采用聚酰胺、硅胶、半制备高效液相色谱等多种色谱技术对化合物进行分离。根据理化性质和光谱数据对化合物的结构进行了鉴定。得到了一对表苯基木脂素苷,7’r -柽柳基醇U 4-O-β-d-葡萄糖吡喃苷(1),7’s -柽柳基醇U 4-O-β-d-葡萄糖吡喃苷(2),以及两个已知化合物3,5,7-三甲氧基黄酮-4’-O-β-d-葡萄糖吡喃苷(3)和selapeptin B(4),其中1和2为新化合物,3和4在甲醇-4中的光谱数据为首次报道。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
3.20
自引率
5.90%
发文量
47
审稿时长
2.3 months
期刊介绍: The Journal of Asian Natural Products Research (JANPR) publishes chemical and pharmaceutical studies in the English language in the field of natural product research on Asian ethnic medicine. The journal publishes work from scientists in Asian countries, e.g. China, Japan, Korea and India, including contributions from other countries concerning natural products of Asia. The journal is chemistry-orientated. Major fields covered are: isolation and structural elucidation of natural constituents (including those for non-medical uses), synthesis and transformation (including biosynthesis and biotransformation) of natural products, pharmacognosy, and allied topics. Biological evaluation of crude extracts are acceptable only as supporting data for pure isolates with well-characterized structures. All published research articles in this journal have undergone rigorous peer review, based on initial editor screening and anonymized refereeing by at least two expert referees.
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