Nonfamilial Unilateral Linear Eccrine Syringofibroadenoma of the Plantar Surface: A Diagnostic Consideration in Acral Eccrine Proliferations.

IF 0.8 4区 医学 Q4 DERMATOLOGY
American Journal of Dermatopathology Pub Date : 2026-09-01 Epub Date: 2026-05-27 DOI:10.1097/DAD.0000000000003329
Jing Xu, Lianjun Chen, Huyan Chen, Shangshang Wang
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引用次数: 0

Abstract

Abstract: Eccrine syringofibroadenoma (ESFA) is an uncommon benign adnexal neoplasm characterized by eccrine ductal differentiation and a distinctive reticulated architectural pattern. The nonfamilial unilateral linear subtype is exceedingly rare and may pose diagnostic difficulty, particularly in acral locations. We describe a long-standing unilateral linear plantar lesion in a middle-aged woman. Histopathological examination revealed anastomosing epithelial cords extending from the epidermis into a fibrovascular stroma, with associated eccrine duct-like structures, consistent with ESFA. Recognition of these characteristic features is essential to distinguish ESFA from other reactive, infectious, and neoplastic eccrine proliferations encountered in dermatopathology practice.

足底表面非家族性单侧线状分泌纤维腺瘤:对肢端分泌增生的诊断考虑。
摘要:内分泌注射器纤维腺瘤(ESFA)是一种少见的良性附件肿瘤,其特征为内分泌导管分化和独特的网状结构。非家族性单侧线性亚型非常罕见,可能造成诊断困难,特别是在肢端位置。我们描述了一个长期单侧线状足底病变在中年妇女。组织病理学检查显示吻合的上皮索从表皮延伸到纤维血管间质,伴有相关的内分泌管样结构,与ESFA一致。识别这些特征对于区分ESFA与皮肤病理学实践中遇到的其他反应性、感染性和肿瘤性内分泌增生至关重要。
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来源期刊
CiteScore
1.80
自引率
9.10%
发文量
453
审稿时长
3 months
期刊介绍: The American Journal of Dermatopathology offers outstanding coverage of the latest diagnostic approaches and laboratory techniques, as well as insights into contemporary social, legal, and ethical concerns. Each issue features review articles on clinical, technical, and basic science advances and illuminating, detailed case reports. With the The American Journal of Dermatopathology you''ll be able to: -Incorporate step-by-step coverage of new or difficult-to-diagnose conditions from their earliest histopathologic signs to confirmatory immunohistochemical and molecular studies. -Apply the latest basic science findings and clinical approaches to your work right away. -Tap into the skills and expertise of your peers and colleagues the world over peer-reviewed original articles, "Extraordinary cases reports", coverage of practical guidelines, and graphic presentations. -Expand your horizons through the Journal''s idea-generating forum for debating controversial issues and learning from preeminent researchers and clinicians
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