Primary Oral MALT Lymphoma Without Nodal or Systemic Involvement: A Rare Presentation.

IF 0.8 4区 医学 Q4 DERMATOLOGY
American Journal of Dermatopathology Pub Date : 2026-09-01 Epub Date: 2026-05-11 DOI:10.1097/DAD.0000000000003318
Elen de Souza Tolentino, Mariane Cordeiro Dos Santos, Ana Regina Casaroto Moreschi, Heliton Gustavo de Lima, Fábio Vieira de Miranda, Camila Lopes Cardoso
{"title":"Primary Oral MALT Lymphoma Without Nodal or Systemic Involvement: A Rare Presentation.","authors":"Elen de Souza Tolentino, Mariane Cordeiro Dos Santos, Ana Regina Casaroto Moreschi, Heliton Gustavo de Lima, Fábio Vieira de Miranda, Camila Lopes Cardoso","doi":"10.1097/DAD.0000000000003318","DOIUrl":null,"url":null,"abstract":"<p><strong>Abstract: </strong>Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) is a low-grade B-cell lymphoma, whose primary manifestation in the oral cavity is exceedingly rare. Owing to its nonspecific clinical presentation and histopathological overlap with benign inflammatory or reactive lesions, the diagnosis of MALT lymphoma can be challenging. We report the case of a middle-aged patient presenting with a slow-growing, asymptomatic oral lesion initially suspected to be an oral lipoma. Histopathological examination, complemented by immunohistochemical analysis, confirmed the diagnosis of primary oral MALT lymphoma. This report highlights the diagnostic challenges associated with oral lymphoid proliferations and underscores the critical importance of clinicopathological correlation for achieving an accurate diagnosis and ensuring appropriate management.</p>","PeriodicalId":50967,"journal":{"name":"American Journal of Dermatopathology","volume":" ","pages":"720-724"},"PeriodicalIF":0.8000,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"American Journal of Dermatopathology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/DAD.0000000000003318","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/5/11 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"DERMATOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Abstract: Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) is a low-grade B-cell lymphoma, whose primary manifestation in the oral cavity is exceedingly rare. Owing to its nonspecific clinical presentation and histopathological overlap with benign inflammatory or reactive lesions, the diagnosis of MALT lymphoma can be challenging. We report the case of a middle-aged patient presenting with a slow-growing, asymptomatic oral lesion initially suspected to be an oral lipoma. Histopathological examination, complemented by immunohistochemical analysis, confirmed the diagnosis of primary oral MALT lymphoma. This report highlights the diagnostic challenges associated with oral lymphoid proliferations and underscores the critical importance of clinicopathological correlation for achieving an accurate diagnosis and ensuring appropriate management.

无淋巴结或全身累及的原发性口腔MALT淋巴瘤:罕见的表现。
摘要:结外粘膜相关淋巴组织边缘区淋巴瘤(MALT淋巴瘤)是一种低级别b细胞淋巴瘤,其主要表现为口腔,极为罕见。由于其非特异性临床表现和与良性炎症或反应性病变的组织病理学重叠,MALT淋巴瘤的诊断可能具有挑战性。我们报告的情况下,中年患者提出了一个缓慢增长,无症状的口腔病变最初怀疑是口腔脂肪瘤。组织病理学检查,辅以免疫组织化学分析,证实了原发性口腔MALT淋巴瘤的诊断。本报告强调了与口腔淋巴细胞增生相关的诊断挑战,并强调了临床病理相关性对于实现准确诊断和确保适当管理的关键重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
1.80
自引率
9.10%
发文量
453
审稿时长
3 months
期刊介绍: The American Journal of Dermatopathology offers outstanding coverage of the latest diagnostic approaches and laboratory techniques, as well as insights into contemporary social, legal, and ethical concerns. Each issue features review articles on clinical, technical, and basic science advances and illuminating, detailed case reports. With the The American Journal of Dermatopathology you''ll be able to: -Incorporate step-by-step coverage of new or difficult-to-diagnose conditions from their earliest histopathologic signs to confirmatory immunohistochemical and molecular studies. -Apply the latest basic science findings and clinical approaches to your work right away. -Tap into the skills and expertise of your peers and colleagues the world over peer-reviewed original articles, "Extraordinary cases reports", coverage of practical guidelines, and graphic presentations. -Expand your horizons through the Journal''s idea-generating forum for debating controversial issues and learning from preeminent researchers and clinicians
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书