Daphne A van Wees, Inge J M Willemstein, Sylvia M Bruisten, Hanneke de Graaf, Koenraad Vermey, Marieke Hiemstra, Birgit H B van Benthem, Janneke C M Heijne
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引用次数: 0
Abstract
Objectives: National prevalence estimates of chlamydia and gonorrhoea are essential to inform public health strategies and support evidence-based policy development. The aim was to generate national prevalence chlamydia and gonorrhoea estimates in 2022/2023, identify associated risk factors and compare prevalence over time.
Methods: Five years after the first survey in 2016/2017, a second national cross-sectional probability sample survey about sexual health among men and women aged 16-34 years in the Netherlands was conducted between October 2022 and March 2023. Sexually active survey participants were invited to participate in the prevalence study and received a home-based sampling kit. Returned samples were tested for chlamydia and gonorrhoea in a laboratory (ie, nucleic acid amplification test). Weighting techniques were used to correct for selective non-response. Multivariable logistic regression analyses were performed to identify risk factors of infection.
Results: Of 6277 survey participants invited for the prevalence study, 1142 (18.2%) returned a specimen. The weighted overall chlamydia prevalence was 3.5% (95% CI 2.3% to 5.4%), and prevalence was higher in younger age groups (<25 vs ≥25 years). Due to low numbers in other groups, risk factor analysis was only possible among women aged 18-24 years, where risk factors for chlamydia included being <20 years, vocational education, no steady relationship and condomless sex. As in 2016/2017, no gonorrhoea cases were detected in 2022/2023. Chlamydia prevalence and associated risk factors did not change, except for higher prevalence among university-educated individuals in 2022/2023.
Discussion: Chlamydia prevalence among young sexually active men and women in the Netherlands remained stable between 2016/2017 and 2022/2023, with higher prevalence observed in younger age groups in both studies. Given recent changes in chlamydia testing guidelines in the Netherlands towards more restrictive testing of asymptomatic individuals, probability sample surveys with laboratory-confirmed STI testing are crucial for monitoring prevalence trends and evaluating public health policy.
目标：衣原体和淋病的国家流行率估计对于为公共卫生战略提供信息和支持基于证据的政策制定至关重要。目的是得出2022/2023年衣原体和淋病的全国流行率估计数，确定相关的风险因素并比较各时期的流行率。方法：在2016/2017年第一次调查五年后，于2022年10月至2023年3月对荷兰16-34岁男性和女性的性健康进行了第二次全国横断面概率抽样调查。性活跃的调查参与者被邀请参加流行病学研究，并收到一套以家庭为基础的抽样工具包。在实验室对返回的样品进行衣原体和淋病检测（即核酸扩增试验）。加权技术用于纠正选择性无反应。进行多变量logistic回归分析以确定感染的危险因素。结果：6277名被邀请参加患病率研究的调查参与者中，1142人（18.2%）返回了样本。衣原体的加权总体患病率为3.5% (95% CI 2.3%至5.4%)，年轻人群的患病率更高（讨论：荷兰年轻性活跃男性和女性的衣原体患病率在2016/2017年至2022/2023年期间保持稳定，两项研究中都观察到年轻人群的患病率较高）。鉴于荷兰衣原体检测指南最近发生了变化，对无症状个体进行了更严格的检测，因此通过实验室确认的性传播感染检测进行概率抽样调查对于监测流行趋势和评估公共卫生政策至关重要。
期刊介绍：
Sexually Transmitted Infections is the world’s longest running international journal on sexual health. It aims to keep practitioners, trainees and researchers up to date in the prevention, diagnosis and treatment of all STIs and HIV. The journal publishes original research, descriptive epidemiology, evidence-based reviews and comment on the clinical, public health, sociological and laboratory aspects of sexual health from around the world. We also publish educational articles, letters and other material of interest to readers, along with podcasts and other online material. STI provides a high quality editorial service from submission to publication.
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