Brain Abscess Treatment Followed by Sinonasal Mucormycosis-Report of Three Cases.

IF 0.8 Q4 CLINICAL NEUROLOGY
Journal of Neurological Surgery Reports Pub Date : 2026-06-11 eCollection Date: 2026-04-01 DOI:10.1055/a-2821-4657
Mohammadreza Firouzifar, Seyed Hadi Samimi Ardestani, Shirin Irani, Maliheh Akbarpour
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引用次数: 0

Abstract

Background Brain abscess following sinonasal mucormycosis is a rare and life-threatening complication. Since our knowledge is mostly based on case reports, a well-documented way of treatment for such cases is yet to be found. Case Description A retrospective case series study was conducted at a tertiary hospital. Patients whose brain abscesses were treated without opening the dura during surgery were selected for the study. The patients received radical debridement of necrotic tissues as well as the infected bones adjacent to the brain abscess. Then, they were treated medically. Three patients were included in the study. All patients had a history of diabetes and COVID-19 before developing symptoms of sinonasal infection. The average size of the abscesses was less than 2 cm. Conclusion Removing infected tissues and bones surrounding the brain abscess without opening the dura can be a viable treatment option for mucormycosis-induced brain abscesses of less than 2 cm.

脑脓肿合并鼻粘膜真菌病治疗3例报告。
背景:鼻粘膜真菌病后脑脓肿是一种罕见且危及生命的并发症。由于我们的知识主要基于病例报告,因此尚未找到一种记录良好的治疗此类病例的方法。病例描述在一家三级医院进行回顾性病例系列研究。在手术中不打开硬脑膜治疗脑脓肿的患者被选为研究对象。患者接受坏死组织和脑脓肿附近感染骨的根治性清创。然后,他们接受了医学治疗。研究中包括3名患者。所有患者在出现鼻窦感染症状前均有糖尿病和COVID-19病史。脓肿的平均大小小于2厘米。结论在不打开硬脑膜的情况下切除脑脓肿周围的感染组织和骨骼是治疗小于2 cm毛霉菌引起的脑脓肿的可行方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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