Valvular Heart Disease in Heart Failure with Preserved Ejection Fraction.

IF 12.2 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS
Cardiac Failure Review Pub Date : 2026-05-27 eCollection Date: 2026-01-01 DOI:10.15420/cfr.2025.13
Athena Adeli, Revathy Sampath-Kumar, Anne Wang, Aristomenis Manouras, Gianluigi Savarese, Rebecca T Hahn, Lars H Lund, Bahira Shahim
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引用次数: 0

Abstract

Heart failure with preserved ejection fraction (HFpEF) is associated with reduced functional capacity and quality of life, as well as with high rates of heart failure hospitalisation and mortality. Valvular heart disease (VHD) is frequently encountered in patients with HFpEF, and both conditions share common risk factors, such as age, hypertension, diabetes and coronary artery disease, which may contribute to their shared pathogenesis and progression. With recent advances in percutaneous therapies for VHD and an improved understanding of HFpEF, there is a growing interest in the relationship between VHD and HFpEF. In this review, we provide an overview of the pathophysiology, epidemiology and management strategies of tricuspid regurgitation, mitral regurgitation, aortic stenosis and aortic regurgitation in the setting of HFpEF.

保留射血分数的心力衰竭患者的瓣膜性心脏病。
心力衰竭伴保留射血分数(HFpEF)与功能能力和生活质量下降以及心力衰竭住院率和死亡率高相关。瓣膜性心脏病(VHD)常见于HFpEF患者,两种疾病具有共同的危险因素,如年龄、高血压、糖尿病和冠状动脉疾病,这可能导致其共同的发病机制和进展。随着VHD经皮治疗的最新进展和对HFpEF的进一步了解,人们对VHD和HFpEF之间的关系越来越感兴趣。在这篇综述中,我们综述了HFpEF患者三尖瓣反流、二尖瓣反流、主动脉狭窄和主动脉反流的病理生理学、流行病学和治疗策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
5.60
自引率
0.00%
发文量
31
审稿时长
9 weeks
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