Nonuniformity in a Certified 68Ge PET Cylinder Phantom: Implications for Normalization Quality Assurance.

IF 1.5 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Subhash Kheruka, Sana Al-Rashdi, Naema Al-Maymani, Anas Al-Balushi, Tasnim Al-Raii, Noura Al-Makhmari, Vipin Jayakrishnan, Anjali Jain, Khulood Al-Riyami, Rashid Al-Sukaiti
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引用次数: 0

Abstract

Quantitative PET imaging depends critically on the accuracy of system normalization and uniformity calibration. We report a manufacturing defect in a certified RadQual 68Ge PET cylinder phantom (BMCY68-2030A-03), a standard reference used for normalization and daily quality control in Siemens Biograph Vision scanners. A localized hot spot was identified within the phantom, producing integral uniformity greater than 8.5% (acceptance limit ≤5%). The nonuniformity was intrinsic to the phantom material and rendered it unsuitable for quantitative use. This finding underscores the importance of independent acceptance testing of long-lived 68Ge standards before clinical deployment to prevent calibration bias and ensure reliable SUV quantification.

经认证的68Ge PET圆柱体模体中的不均匀性:标准化质量保证的含义。
定量PET成像关键取决于系统归一化和均匀性校准的准确性。我们报告了经认证的RadQual 68Ge PET圆柱体(BMCY68-2030A-03)的制造缺陷,该圆柱体是西门子Biograph Vision扫描仪规范化和日常质量控制的标准参考。在体模内发现局部热点,整体均匀度大于8.5%(接受极限≤5%)。这种不均匀性是模体材料固有的,不适合定量使用。这一发现强调了在临床部署之前对长寿命68Ge标准进行独立验收测试的重要性,以防止校准偏差并确保可靠的SUV量化。
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来源期刊
Journal of nuclear medicine technology
Journal of nuclear medicine technology RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
1.90
自引率
15.40%
发文量
57
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